Goat anti-Human, Mouse SDPR Polyclonal Antibody | anti-SDPR antibody

SDPR (Serum deprivation response (phosphatidylserine binding protein), cavin-2, Phosphatidylserine-binding protein, PS-p68, SDR, Serum deprivation-response protein)

Cat. Num. AAA622385

• Gene Names: SDPR; SDR; CAVIN2; PS-p68; cavin-2
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: SDPR; Polyclonal Antibody; SDPR (Serum deprivation response (phosphatidylserine binding protein); cavin-2; Phosphatidylserine-binding protein; PS-p68; SDR; Serum deprivation-response protein); Anti -SDPR (Serum deprivation response (phosphatidylserine binding protein); anti-SDPR antibody

• Host: Goat
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human SDPR. Species Crossreactivity: mouse.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a lyophilized powder from 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with sterile PBS, sterile 40-50% glycerol.

• Applicable Applications for anti-SDPR antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in ELISA and Western Blot.; Dilution: Western Blot: 1ug/ml; ELISA: 0.5-1ug/ml
• Immunogen: Recombinant human SDPR, aa2-180.
• Preparation and Storage: Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS, sterile 40-50% glycerol, aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for anti-SDPR antibody

SDPR (Serum deprivation response gene; also SDR and PS-p68) is a 68-70kD member of the PTRF/SDPR family of proteins. It is expressed in striated muscle, platelets, and fibroblasts, and is cytosolic in location. SDPR is known to bind phosphatidylserine and form complexes with both PKC alpha and PTRF, targeting them to caveolae. Human SDPR is 425 amino acids in

Product Categories/Family for anti-SDPR antibody

Antibodies; Abs to Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 4759082
• NCBI GeneID: 8436
• NCBI Accession #: NP_004648.1
• NCBI GenBank Nucleotide #: NM_004657.5
• UniProt Accession #: O95810
• Molecular Weight: 47,173 Da
• NCBI Official Full Name: serum deprivation-response protein
• NCBI Official Synonym Full Names: serum deprivation response
• NCBI Official Symbol: SDPR
• NCBI Official Synonym Symbols: SDR; CAVIN2; PS-p68; cavin-2
• NCBI Protein Information: serum deprivation-response protein; OTTHUMP00000205484; phosphatidylserine binding protein; phosphatidylserine-binding protein
• UniProt Protein Name: Serum deprivation-response protein
• Protein Family: Serum deprivation-response protein
• UniProt Gene Name: SDPR
• UniProt Entry Name: SDPR_HUMAN

NCBI Description

This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.

Uniprot Description

SDPR: May play a role in targeting PRKCA to caveolae. Belongs to the PTRF/SDPR family.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 2q32-q33

Cellular Component: cytoplasm; caveola; cytosol

Molecular Function: protein binding; protein kinase C binding; phosphatidylserine binding; phospholipid binding