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Rabbit anti-Human Nucleolar Protein, 30kD Polyclonal Antibody

Nucleolar Protein, 30kD (Nop30, Apoptosis Repressor with CARD, ARC, Muscle-enriched Cytoplasmic Protein, Myp, Nucleolar Protein 3)

Reactivity
Human
Applications
Western Blot
Purity
Purified
Purified
Synonyms
Nucleolar Protein; 30kD; Polyclonal Antibody; 30kD (Nop30; Apoptosis Repressor with CARD; ARC; Muscle-enriched Cytoplasmic Protein; Myp; Nucleolar Protein 3); Anti -Nucleolar Protein; anti-Nucleolar Protein; 30kD antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
This antibody is specific for the human Nop30 protein. Species Crossreactivity: Reacts with residues 125-141 (PELQTLTRPGALRAPRR) of the human Nop30 protein. Reactivity to other species has not tested.
Purity/Purification
Purified
Purified
Applicable Applications for anti-Nucleolar Protein, 30kD antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
A synthetic peptide made to residues 125-141 (PELQTLTRPGALRAPRR) of the human Nop30 protein.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Nucleolar Protein, 30kD antibody
Nop30 (nucleolar protein of 30kD) is predominantly expressed in muscle and is present in the nucleoplasm and concentrated in nucleoli. The predominant nucleolar localization of Nop30 points to a potential role in RNA processing in muscle nucleoli. A CARD domain containing protein, designated ARC for apoptosis repressor with CARD is related to Nop30 with a different carboxyl terminus.
Product Categories/Family for anti-Nucleolar Protein, 30kD antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI Official Full Name
nucleolar protein

Uniprot Description

MCRS1: Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; RNA-binding; Nucleolus

Chromosomal Location of Human Ortholog: 12q13.12

Cellular Component: nucleoplasm; cytoplasm; nucleolus; cell junction; histone acetyltransferase complex; actin cytoskeleton

Molecular Function: protein binding; histone acetyltransferase activity (H4-K16 specific)

Biological Process: establishment and/or maintenance of chromatin architecture; regulation of transcription, DNA-dependent; transcription, DNA-dependent; protein modification process; DNA repair; DNA recombination

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Product Notes

The Nucleolar Protein, 30kD (Catalog #AAA619768) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Nucleolar Protein, 30kD (Nop30, Apoptosis Repressor with CARD, ARC, Muscle-enriched Cytoplasmic Protein, Myp, Nucleolar Protein 3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Nucleolar Protein, 30kD can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the Nucleolar Protein, 30kD for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Nucleolar Protein, 30kD, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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