Rabbit anti-Human Formyl Peptide Receptor-like 1 Polyclonal Antibody | anti-FPR2 antibody

Formyl Peptide Receptor-like 1 (FPRL1, Formyl Peptide Receptor 2, FPR2, FMLP R I, FMLP R II, FMLP-related Receptor I, FMLPX, FPR2A, FPRH1, FPRH2, HM63, Lipoxin A4 Receptor, LXA4 Receptor, LXA4R, RFP)

Cat. Num. AAA619362

• Gene Names: FPR2; ALXR; HM63; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; LXA4R; FMLP-R-II
• Reactivity: Human
• Applications: Western Blot, Immunofluorescence
• Purity: Affinity Purified; Purified by Protein G affinity chromatography.
• Synonyms: Formyl Peptide Receptor-like 1; Polyclonal Antibody; Formyl Peptide Receptor-like 1 (FPRL1; Formyl Peptide Receptor 2; FPR2; FMLP R I; FMLP R II; FMLP-related Receptor I; FMLPX; FPR2A; FPRH1; FPRH2; HM63; Lipoxin A4 Receptor; LXA4 Receptor; LXA4R; RFP); Anti -Formyl Peptide Receptor-like 1 (FPRL1; anti-FPR2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human Formyl Peptide Receptor-like 1 (FPRL1).
• Purity/Purification: Affinity Purified; Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a lyophilized powder from PBS, pH 7.4. Reconstitute with 100ul sterile ddH2O.

• Applicable Applications for anti-FPR2 antibody: Western Blot (WB), Immunofluorescence (IF)
• Application Notes: Suitable for use in Immunofluorescence and Western Blot.; Dilution: Immunofluorescence: 1:600; Western Blot: 1:6000
• Immunogen: Synthetic peptide corresponding to the C-terminal of human FPRL1 (KLH).
• Positive Control: HL-60
• Preparation and Storage: Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Western Blot (WB)

(Western Blot analysis of extracts from HL-60 cells using MBS619362. Band at ~38kD.)

Immunofluorescence (IF)

(Immunofluorescent analysis of HL-60 cells using MBS619362 (green). Nuclei have been labeled with Pi (red).)

Product Categories/Family for anti-FPR2 antibody

Antibodies; Abs to Receptors

NCBI and Uniprot Product Information

• NCBI GI #: 29293107
• NCBI GeneID: 2358
• UniProt Accession #: P25090; A8K3E2; AAB23104
• Molecular Weight: 38,964 Da
• NCBI Official Full Name: formyl peptide receptor-like 1
• NCBI Official Synonym Full Names: formyl peptide receptor 2
• NCBI Official Symbol: FPR2
• NCBI Official Synonym Symbols: ALXR; HM63; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; LXA4R; FMLP-R-II
• NCBI Protein Information: N-formyl peptide receptor 2; RFP; FMLP-R-I; LXA4 receptor; FMLP-related receptor I; formyl peptide receptor-like 1; lipoxin A4 receptor (formyl peptide receptor related)
• UniProt Protein Name: N-formyl peptide receptor 2
• Protein Family: Formyl peptide receptor
• UniProt Gene Name: FPR2
• UniProt Synonym Gene Names: FPRH1; FPRL1; LXA4R
• UniProt Entry Name: FPR2_HUMAN

Uniprot Description

FPR2: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). Belongs to the G-protein coupled receptor 1 family.

Protein type: Motility/polarity/chemotaxis; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1

Chromosomal Location of Human Ortholog: 19q13.3-q13.4

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; N-formyl peptide receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; inflammatory response; cell adhesion; chemotaxis; cell motility