Western Blot (WB)
(Western Blot: E. coli-derived fusion protein as test antigen. MBS614642 dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development (anti-RGS12).)
Chicken RGS12 Polyclonal Antibody | anti-RGS12 antibody
RGS12 (Regulator of G Protein Signaling 12, DKFZp761K1617, DKFZp761K1817)
Other applications not tested.
Dilution:
Western Blot: 1:2000. Predicted MW: 174kD
Optimal dilutions to be determined by the researcher.
Western Blot (WB)
(Western Blot: E. coli-derived fusion protein as test antigen. MBS614642 dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development (anti-RGS12).)
Western Blot (WB)
(Western Blot: E. coli-derived fusion protein as test antigen. MBS614642 dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development (anti-RGS12).)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq]
Uniprot Description
RGS12: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs, misc.; GAPs
Chromosomal Location of Human Ortholog: 4p16.3
Cellular Component: nuclear matrix; condensed nuclear chromosome; cytoplasm; nucleolus; plasma membrane; nucleus
Molecular Function: receptor signaling protein activity; GTPase regulator activity; GTPase activator activity
Biological Process: transcription, DNA-dependent; regulation of catalytic activity; regulation of G-protein coupled receptor protein signaling pathway; positive regulation of GTPase activity
Research Articles on RGS12
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Product Notes
The RGS12 rgs12 (Catalog #AAA614642) is an Antibody produced from Chicken and is intended for research purposes only. The product is available for immediate purchase. The RGS12 (Regulator of G Protein Signaling 12, DKFZp761K1617, DKFZp761K1817) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RGS12 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot Other applications not tested. Dilution: Western Blot: 1:2000. Predicted MW: 174kD Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the RGS12 rgs12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RGS12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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