NCBI Description
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1. [provided by RefSeq, Jul 2008]
Uniprot Description
CELA3A: Efficient protease with alanine specificity but only little elastolytic activity. Belongs to the peptidase S1 family. Elastase subfamily.
Protein type: Protease; EC 3.4.21.70
Chromosomal Location of Human Ortholog: 1p36.12
Molecular Function: serine-type endopeptidase activity
Biological Process: cholesterol metabolic process; digestion; proteolysis
Product Notes
The Cat ELA3A cela3a (Catalog #
AAA060982) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA060982 ELISA Kit recognizes Cat ELA3A.
It is sometimes possible for the material contained within the vial of
"Elastase 3A, ELISA Kit" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
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purchaser may be intending to use a product outside of our accepted criteria.
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