Rabbit Cystatin C Polyclonal Antibody | anti-CST3 antibody

Cystatin C Antibody

• Gene Names: CST3; ARMD11; HEL-S-2
• Applications: Western Blot, Immunohistochemistry, Immunocytochemistry
• Purity: Affinity Chromatography
• Synonyms: Cystatin C; Polyclonal Antibody; Cystatin C Antibody; Affinity Purified Goat Polyclonal Cystatin C Antibody; Polyclonal Cystatin C antibody; Anti-Cystatin C antibody; anti-CST3 antibody

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Chromatography
• Form/Format: Lyophilized Form
• Sequence Length: 146

• Applicable Applications for anti-CST3 antibody: Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC)
• Immunogen: Cystatin C antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human Cystatin C as the immunogen
• Preparation and Storage: Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded section of Human Mammary Cancer Tissue)

Western Blot (WB)

(Lane 1: Recombinant Human Cystatin C Protein 10ng, Lane 2: Recombinant Human Cystatin C Protein 5ng; Lane 3: Recombinant Human Cystatin C Protein 2.5ng)

Related Product Information for anti-CST3 antibody

Cystatin C or cystatin 3 (formerly gamma trace, post-gamma-globulin or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease.

Product Categories/Family for anti-CST3 antibody

Cardiac Markers

NCBI and Uniprot Product Information

• NCBI GI #: 755738
• NCBI GeneID: 1471
• NCBI Official Full Name: cystatin C
• NCBI Official Synonym Full Names: cystatin C
• NCBI Official Symbol: CST3
• NCBI Official Synonym Symbols: ARMD11; HEL-S-2
• NCBI Protein Information: cystatin-C
• Protein Family: Cystatin

NCBI Description

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus. Alternative splicing results in multiple transcript variants encoding a single protein. [provided by RefSeq, Nov 2014]