Western Blot (WB)
(Western Blot analysis in mouse stonach tissue lysates (35ug/lane) using MBS6013042. This demonstrates that MBS6013042 detected LRRC16A protein (arrow).)
Rabbit anti-Human, Mouse LRRC16A Polyclonal Antibody | anti-LRRC16A antibody
LRRC16A, CT (LRRC16A, CARMIL, LRRC16, Leucine-rich repeat-containing protein 16A, CARMIL homolog)
Gene Names
LRRC16A; CARMIL; LRRC16; CARMIL1; CARMIL1a; dJ501N12.1; dJ501N12.5
Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
LRRC16A; Polyclonal Antibody; CT (LRRC16A; CARMIL; LRRC16; Leucine-rich repeat-containing protein 16A; CARMIL homolog); Anti -LRRC16A; anti-LRRC16A antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Human, mouse
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-LRRC16A antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunogen
LRRC16A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1151-1178 amino acids from the C-terminal region of human LRRC16A.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis in mouse stonach tissue lysates (35ug/lane) using MBS6013042. This demonstrates that MBS6013042 detected LRRC16A protein (arrow).)
Western Blot (WB)
(Western Blot analysis in mouse stonach tissue lysates (35ug/lane) using MBS6013042. This demonstrates that MBS6013042 detected LRRC16A protein (arrow).)
Related Product Information for anti-LRRC16A antibody
LRRC16A binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity).
Product Categories/Family for anti-LRRC16A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
151,557 Da
NCBI Official Full Name
LRRC16A protein
NCBI Official Synonym Full Names
leucine rich repeat containing 16A
NCBI Official Symbol
LRRC16A
NCBI Official Synonym Symbols
CARMIL; LRRC16; CARMIL1; CARMIL1a; dJ501N12.1; dJ501N12.5
NCBI Protein Information
leucine-rich repeat-containing protein 16A; CARMIL homolog; leucine rich repeat containing 16; capping protein, Arp2/3, and Myosin-I Linker homolog 1
UniProt Protein Name
Leucine-rich repeat-containing protein 16A
Protein Family
UniProt Gene Name
LRRC16A
UniProt Synonym Gene Names
CARMIL; CARMIL1a; LRRC16
UniProt Entry Name
LR16A_HUMAN
Uniprot Description
LRRC16: Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization. Belongs to the CARMIL family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 6p22.2
Cellular Component: filamentous actin; lamellipodium; cytoplasm; nucleus; cytosol
Molecular Function: protein complex binding
Biological Process: lamellipodium biogenesis; cell migration; urate metabolic process; positive regulation of actin filament polymerization; positive regulation of stress fiber formation; ruffle organization and biogenesis; actin filament organization; barbed-end actin filament uncapping; blood coagulation; positive regulation of cell migration
Research Articles on LRRC16A
Similar Products
Product Notes
The LRRC16A lrrc16a (Catalog #AAA6013042) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LRRC16A, CT (LRRC16A, CARMIL, LRRC16, Leucine-rich repeat-containing protein 16A, CARMIL homolog) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LRRC16A can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the LRRC16A lrrc16a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRRC16A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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