Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 46601(LRRC16A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
Rabbit anti-Human LRRC16A Polyclonal Antibody | anti-LRRC16A antibody
LRRC16A Antibody
Gene Names
CARMIL1; CARMIL; LRRC16; LRRC16A; CARMIL1a; dJ501N12.1; dJ501N12.5
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
LRRC16A; Polyclonal Antibody; LRRC16A Antibody; CARMIL; LRRC16; CARMIL1; CARMIL1a; dJ501N12.1; dJ501N12.5; anti-LRRC16A antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total LRRC16A protein.
Purity/Purification
Antigen affinity purification
Form/Format
In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
1371
Applicable Applications for anti-LRRC16A antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1: 30-150
Immunogen
Synthetic peptide corresponding to residues near the C terminal of human LRRC16A
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 46601(LRRC16A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 46601(LRRC16A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
Related Product Information for anti-LRRC16A antibody
Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed:16054028). Plays a role in lamellipodial protrusion formations and cell migration (PubMed:19846667).
Product Categories/Family for anti-LRRC16A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,181 Da
NCBI Official Full Name
F-actin-uncapping protein LRRC16A isoform 1
NCBI Official Synonym Full Names
capping protein regulator and myosin 1 linker 1
NCBI Official Symbol
CARMIL1
NCBI Official Synonym Symbols
CARMIL; LRRC16; LRRC16A; CARMIL1a; dJ501N12.1; dJ501N12.5
NCBI Protein Information
F-actin-uncapping protein LRRC16A
UniProt Protein Name
F-actin-uncapping protein LRRC16A
Protein Family
UniProt Gene Name
CARMIL1
Uniprot Description
Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed:16054028). Plays a role in lamellipodial protrusion formations and cell migration (PubMed:19846667).
Research Articles on LRRC16A
Similar Products
Product Notes
The LRRC16A carmil1 (Catalog #AAA9429748) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LRRC16A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LRRC16A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1: 30-150. Researchers should empirically determine the suitability of the LRRC16A carmil1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRRC16A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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