Rat anti-Mouse PTX3 Monoclonal Antibody | anti-PTX3 antibody

PTX3 (Long Pentraxin, TSG14)

Cat. Num. AAA601109

• Gene Names: PTX3; TSG-14; TNFAIP5
• Reactivity: Mouse
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein G affinity chromatography.
• Synonyms: PTX3; Monoclonal Antibody; PTX3 (Long Pentraxin; TSG14); Anti -PTX3 (Long Pentraxin; anti-PTX3 antibody

• Host: Rat
• Reactivity: Mouse
• Clonality: Monoclonal
• Isotype: IgG2a
• Clone Number: 7H62
• Specificity: Recognizes mouse PTX3.
• Purity/Purification: Affinity Purified; Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile ddH2O or sterile 40-50% glycerol.

• Applicable Applications for anti-PTX3 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot and ELISA.
• Immunogen: NS0-derived recombinant mouse PTX3 (aa18-381) Accession # P48759
• Preparation and Storage: Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for anti-PTX3 antibody

Pentraxin 3 (PTX3), also known as TSG-14, belongs to the pentraxin family, which was named originally for the homopentameric structure formed by its members. PTX3/TSG-14 is a long pentraxin that contains a pentraxin-like domain at its carboxy-terminus with amino acid sequence similarity with short pentraxins (C-reactive protein and serum amyloid P component). PTX3 is a marker of the acute phase response and is highly expressed in advanced atherosclerotic plaques.

Product Categories/Family for anti-PTX3 antibody

Antibodies; Abs to Transcription Factors

NCBI and Uniprot Product Information

• NCBI GI #: 167900484
• NCBI GeneID: 5806
• NCBI Accession #: NP_002843.2
• NCBI GenBank Nucleotide #: NM_002852.3
• UniProt Accession #: P26022; Q38M82; B2R6T6
• Molecular Weight: 41,976 Da
• NCBI Official Full Name: pentraxin-related protein PTX3
• NCBI Official Synonym Full Names: pentraxin 3, long
• NCBI Official Symbol: PTX3
• NCBI Official Synonym Symbols: TSG-14; TNFAIP5
• NCBI Protein Information: pentraxin-related protein PTX3; pentraxin-3; OTTHUMP00000213379; TNF alpha-induced protein 5; pentaxin-related protein PTX3; tumor necrosis factor alpha-induced protein 5; tumor necrosis factor, alpha-induced protein 5; tumor necrosis factor-inducible protein TSG-14; tumor necrosis factor-inducible gene 14 protein; pentraxin-related gene, rapidly induced by IL-1 beta; pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, alpha-induced protein 5
• UniProt Protein Name: Pentraxin-related protein PTX3
• Protein Family: Pentraxin-related protein
• UniProt Gene Name: PTX3
• UniProt Synonym Gene Names: TNFAIP5; TSG14
• UniProt Entry Name: PTX3_HUMAN

Uniprot Description

PTX3: Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self- components and female fertility.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 3q25

Cellular Component: extracellular space; extracellular region

Molecular Function: complement component C1q binding; zymosan binding; virion binding

Biological Process: positive regulation of nitric oxide biosynthetic process; negative regulation of virion penetration into host cell; positive regulation of phagocytosis; innate immune response; response to yeast; opsonization; inflammatory response