Immunohistochemistry (IHC)
(Immunohistochemistry analysis of brain tissue from APP Tg2576 transgenic mouse probed with MBS6010699. Paraformaldehyde fixed sections were pretreated with 70% formic acid for 5 minutes followed by steaming for 30 minutes and blocked with normal goat serum (no need for antigen retrieval if fresh or frozen sections are used). Sections were incubated with MBS6010699 at 0.5ug/ml overnight. Immunoreactivity was visualized using DAKO Envision HRP System (1:10,000 dilution).)
Mouse Amyloid Beta, 1-40 Monoclonal Antibody
Amyloid Beta, 1-40 (Amyloid A4)
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
PurifiedPurified
Synonyms
Amyloid Beta; 1-40; Monoclonal Antibody; 1-40 (Amyloid A4); Anti -Amyloid Beta; anti-Amyloid Beta; 1-40 antibody
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
MM32-13.1.1
Specificity
Recognizes beta-amyloid. Species Crossreactivity: human, mouse and rat.
Purity/Purification
Purified
Purified
Purified
Form/Format
Supplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.1% sodium azide, 50% glycerol.
Applicable Applications for anti-Amyloid Beta, 1-40 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot: 0.5-1ug/ml
Immunohistochemistry: 0.5-1ug/ml
Dilution: Western Blot: 0.5-1ug/ml
Immunohistochemistry: 0.5-1ug/ml
Immunogen
Synthetic peptide corresponding to aa35-40 (MVGGVV) of beta-amyloid (1-40).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of brain tissue from APP Tg2576 transgenic mouse probed with MBS6010699. Paraformaldehyde fixed sections were pretreated with 70% formic acid for 5 minutes followed by steaming for 30 minutes and blocked with normal goat serum (no need for antigen retrieval if fresh or frozen sections are used). Sections were incubated with MBS6010699 at 0.5ug/ml overnight. Immunoreactivity was visualized using DAKO Envision HRP System (1:10,000 dilution).)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of brain tissue from APP Tg2576 transgenic mouse probed with MBS6010699. Paraformaldehyde fixed sections were pretreated with 70% formic acid for 5 minutes followed by steaming for 30 minutes and blocked with normal goat serum (no need for antigen retrieval if fresh or frozen sections are used). Sections were incubated with MBS6010699 at 0.5ug/ml overnight. Immunoreactivity was visualized using DAKO Envision HRP System (1:10,000 dilution).)
Related Product Information for anti-Amyloid Beta, 1-40 antibody
Alzheimer's Disease (AD) is the most common neurodenerative disorder in elderly people. It has been demonstrated that AD has biological cause and is characterized by the presence of senile plaques and neurofibrillary tangles mainly in cerebral cortex and hippocampus brain regions. beta-Amyloid 1-40 (Ab40) and beta-amyloid 1-42 (Ab42) are the main components of the above plaques; however, other forms of amyloid-beta peptides also present. Both peptides are cleaved from the Amyloid Precursor Protein (APP) by b-secretase and g-secretase enzymes. Many studies suggest that Ab42 or/and Ab43 are required to initiate formation of amyloid plaques and neurofibrills that leads to the neurodegeneration while Ab40 is less neurotoxic.
Product Categories/Family for anti-Amyloid Beta, 1-40 antibody
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Product Notes
The Amyloid Beta, 1-40 (Catalog #AAA6010699) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Amyloid Beta, 1-40 (Amyloid A4) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Amyloid Beta, 1-40 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot and Immunohistochemistry. Dilution: Western Blot: 0.5-1ug/ml Immunohistochemistry: 0.5-1ug/ml. Researchers should empirically determine the suitability of the Amyloid Beta, 1-40 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Amyloid Beta, 1-40, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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