Mouse anti-Rat Neurite Outgrowth Inhibitor A Monoclonal Antibody | anti-RTN4 antibody
Neurite Outgrowth Inhibitor A (NogoA)
Gene Names
RTN4; NOGO; NOGO-A; RTN4
Reactivity
Rat
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
Neurite Outgrowth Inhibitor A; Monoclonal Antibody; Neurite Outgrowth Inhibitor A (NogoA); Anti -Neurite Outgrowth Inhibitor A (NogoA); anti-RTN4 antibody
Host
Mouse
Reactivity
Rat
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
7H189
Specificity
Recognizes rat NOGO-A.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile ddH2O or sterile 40-50% glycerol.
Applicable Applications for anti-RTN4 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Western Blot and ELISA.
Immunogen
E. coli-derived recombinant rat NOGO-A (aa2-172) Accession # NP_114019
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-RTN4 antibody
Nogo-A, also known as Reticulon-4, is the longest of four splice variants of Nogo. It is a CNS myelin-associated neurite outgrowth inhibitor that is highly expressed in oligodendrocytes. Nogo-A is synthesized as an 1163 amino acid protein and lacks a signal peptide. Within conserved C-terminal reticulon homology domain (RHD), two transmembrane domains, which are separated by a 66 amino acid extracellular loop, exist. Both the N-terminal domain and the 66 amino acid domain (Nogo-66) can be detected on the cell surface and show neurite outgrowth inhibitory activity. The amino acid sequence of rat Nogo-A N-terminal domain is 76% identical to that of human Nogo-A. Within the RHD domain, rat Nogo-A shares 99% and 97% amino acid sequence identity with mouse and human Nogo, respectively.
Product Categories/Family for anti-RTN4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
72,076 Da
NCBI Official Full Name
neurite outgrowth inhibitor NOGO-A
NCBI Official Synonym Full Names
reticulon 4
NCBI Official Symbol
RTN4
NCBI Official Synonym Symbols
NOGO; NOGO-A; RTN4
NCBI Protein Information
reticulon-4; neurite outgrowth inhibitor
UniProt Protein Name
Neurite outgrowth inhibitor NOGO-A
Protein Family
UniProt Gene Name
NOGO
UniProt Entry Name
Q6RSS8_CHICK
Research Articles on RTN4
Similar Products
Product Notes
The RTN4 nogo (Catalog #AAA601064) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Neurite Outgrowth Inhibitor A (NogoA) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Neurite Outgrowth Inhibitor A can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot and ELISA. Researchers should empirically determine the suitability of the RTN4 nogo for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Neurite Outgrowth Inhibitor A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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