Rabbit anti-Human GPRC5C Polyclonal Antibody | anti-GPRC5C antibody

GPRC5C, CT (G-protein Coupled Receptor Family C Group 5 Member C, Retinoic Acid-induced Gene 3 Protein, RAIG-3, RAIG3, PSEC0087)

Cat. Num. AAA6010206

• Gene Names: GPRC5C; RAIG3; RAIG-3
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: GPRC5C; Polyclonal Antibody; CT (G-protein Coupled Receptor Family C Group 5 Member C; Retinoic Acid-induced Gene 3 Protein; RAIG-3; RAIG3; PSEC0087); Anti -GPRC5C; anti-GPRC5C antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: Recognizes human GPRC5C. Species sequence homology: mouse (94%).
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.1% sodium azide.

• Applicable Applications for anti-GPRC5C antibody: Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Immunohistochemistry.; Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
• Immunogen: Synthetic peptide corresponding to 19aa from C-terminal cytoplasmic domain of human GPRC5C.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Adrenal (formalin-fixed, paraffin-embedded) stained with GPRC5C antibody at 10ug/ml followed by biotinylated goat rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.)

Related Product Information for anti-GPRC5C antibody

GPRC5C is an Orphan-C GPCR induced by retinoids.

Product Categories/Family for anti-GPRC5C antibody

Antibodies; Abs to G Protein Receptors

NCBI and Uniprot Product Information

• NCBI GI #: 40217833
• NCBI GeneID: 55890
• NCBI Accession #: NP_061123.3
• NCBI GenBank Nucleotide #: NM_018653.3
• UniProt Accession #: Q9NQ84; Q2NL85; Q9NZG5; B5BUN4
• Molecular Weight: 48,193 Da
• NCBI Official Full Name: G-protein coupled receptor family C group 5 member C isoform b
• NCBI Official Synonym Full Names: G protein-coupled receptor, family C, group 5, member C
• NCBI Official Symbol: GPRC5C
• NCBI Official Synonym Symbols: RAIG3; RAIG-3
• NCBI Protein Information: G-protein coupled receptor family C group 5 member C; orphan G-protein coupled receptor; retinoic acid-induced gene 3 protein; retinoic acid responsive gene protein
• UniProt Protein Name: G-protein coupled receptor family C group 5 member C
• Protein Family: G-protein coupled receptor family
• UniProt Gene Name: GPRC5C
• UniProt Synonym Gene Names: RAIG3; RAIG-3
• UniProt Entry Name: GPC5C_HUMAN

NCBI Description

The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

GPRC5C: This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Belongs to the G-protein coupled receptor 3 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GPCR, family 3; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: cytoplasmic vesicle membrane; mitochondrion; integral to plasma membrane; vesicle; receptor complex

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway