Mouse HCV, NS3 Monoclonal Antibody
HCV, NS3 (Nonstructural Protein 3)
Applications
Western Blot, Immunocytochemistry
Purity
Highly Purified>95% (SDS-PAGE)
Synonyms
HCV; NS3; Monoclonal Antibody; NS3 (Nonstructural Protein 3); Anti -HCV; anti-HCV; NS3 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1B6
Specificity
Recognizes HCV NS3 (genotype 1a and 1b) (epitope mapped to NS3 aa 160-193), recognizes NS3 alone or the NS3-4A complex. Does not cross-react with HCV NS3 (genotype 2a). t
Purity/Purification
Highly Purified
>95% (SDS-PAGE)
>95% (SDS-PAGE)
Form/Format
Supplied as a liquid in PBS, 10% glycerol, 0.02% sodium azide.
Applicable Applications for anti-HCV, NS3 antibody
Western Blot (WB), Immunocytochemistry (ICC)
Application Notes
Suitable for use in Immunocytochemistry, Western Blot
Immunogen
Recombinant hepatitis C virus (HCV) NS3 serine protease domain.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-HCV, NS3 antibody
The NS3 serine protease, in association with NS4A, is responsible for the cleavages of the Hepatitis C virus protease complexes NS3-NS4A, NS4A-NS4B, NS4B-NS5A and NS5A-NS5B. NS5B is a RNA-dependent RNA polymerase that plays an essential role in the virus replication. Hepatitis C virus protease NS3-NS4A colocalizes with IPS-1/VISA/MAVS/Cardif in the mitochondrial membrane and has been shown to cleave the TLR3 adapter TRIF and Cardif to eliminate the antiviral signaling pathways. NS3-NS4A represents an important target for anti-HCV drugs.
Product Categories/Family for anti-HCV, NS3 antibody
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Product Notes
The HCV, NS3 (Catalog #AAA6005470) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's HCV, NS3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). Suitable for use in Immunocytochemistry, Western Blot. Researchers should empirically determine the suitability of the HCV, NS3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HCV, NS3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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