Mouse HIRA Interacting Protein 3 Monoclonal Antibody | anti-HIRIP3 antibody

HIRA Interacting Protein 3 (HIRIP3)

Cat. Num. AAA600545

• Gene Names: HIRIP3; HIRIP3
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein G affinity chromatography.
• Synonyms: HIRA Interacting Protein 3; Monoclonal Antibody; HIRA Interacting Protein 3 (HIRIP3); Anti -HIRA Interacting Protein 3 (HIRIP3); anti-HIRIP3 antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 8C178
• Specificity: Recognizes human HIRA Interacting Protein 3.
• Purity/Purification: Affinity Purified; Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.

• Applicable Applications for anti-HIRIP3 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blotting.; Dilution: Western Blotting: 1:1000-1:2000
• Immunogen: Partial sequence of recombinant full-length protein to human HIRA Interacting Protein 3
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Testing Data

Product Categories/Family for anti-HIRIP3 antibody

Antibodies; Abs to Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 21396500
• NCBI GeneID: 8479
• NCBI Accession #: NP_003600.2
• NCBI GenBank Nucleotide #: NM_003609.4
• UniProt Accession #: Q9BW71; O75707; O75708
• Molecular Weight: 61,957 Da
• NCBI Official Full Name: HIRA-interacting protein 3
• NCBI Official Synonym Full Names: HIRA interacting protein 3
• NCBI Official Symbol: HIRIP3
• NCBI Official Synonym Symbols: HIRIP3
• NCBI Protein Information: HIRA-interacting protein 3; OTTHUMP00000162998
• UniProt Protein Name: HIRA-interacting protein 3
• Protein Family: HIRA-interacting protein
• UniProt Gene Name: HIRIP3
• UniProt Entry Name: HIRP3_HUMAN

NCBI Description

The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Recently, several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the HIRIP3 gene product binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq]

Uniprot Description

HIRIP3: May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: nucleoplasm; nucleolus; nucleus

Molecular Function: protein binding

Biological Process: chromatin assembly or disassembly