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Mouse H-FABP Monoclonal Antibody | anti-H-FABP antibody

H-FABP, Human, mAb 67D3

Reactivity
Reactivity: Human. Cross reactivity: Mouse, Rat
Applications
Immunoprecipitation, Western Blot
Synonyms
H-FABP; Monoclonal Antibody; Human; mAb 67D3; Fatty acid-binding protein 3; FABP3; Muscle fatty acid-binding protein; Mammary-derived growth inhibitor; anti-H-FABP antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Reactivity: Human. Cross reactivity: Mouse, Rat
Clonality
Monoclonal
Isotype
Mouse IgG1
Form/Format
1 ml (100 ug/ml) 0.2 um filtered antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide.
For unit size 0.5 mg or larger: PBS only (concentration< 0.5mg/ml)
Sequence Length
133
Applicable Applications for anti-H-FABP antibody
Immunoassay (IA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
Application Notes: IP: Biotinylated 67D3 was immobilized on streptavidin beads and added to serum to immunoprecipitate H-FABP (Ref.3).
Application Use: For immunohistology and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
Immunogen
Purified Human H-FABP
Positive Control
Heart cells, recombinant human H-FABP
Preparation and Storage
Product should be stored at 4 degree C. Under recommended storage conditions, product is stable for one year.
Related Product Information for anti-H-FABP antibody
Product Description: The monoclonal antibody 67D3 recognizes human heart-type fatty acid-binding protein (H-FABP) of both natural and recombinant origin. The H-FABP protein is derived from the human FABP3 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. H-FABP is localized in the heart, skeletal and smooth muscle, mammary epithelial cells, aorta, distal tubules of the kidney, lung, brain, placenta, and ovary. Furthermore, this antibody is useful for the purification of H-FABP.
References
1. Roos, W et al; Monoclonal antibodies to human heart fatty acid-binding protein. J Immunol Meth 1995, 183: 149 2. Pelsers, M et al; Brain- and heart-type fatty acid-binding proteins in the brain: tissue distribution and clinical utility. Clin Chem 2004, 50: 1568
3. Zhen, E et al; Quantification of heart fatty acid binding protein as a biomarker for drug-induced cardiac and musculoskeletal necrosis. Proteomics Clin Appl 2007, 1: 661

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
heart-type fatty acid binding protein
NCBI Official Symbol
H-FABP
NCBI Protein Information
heart-type fatty acid binding protein; fatty acid-binding protein; fatty acid binding protein 3

Research Articles on H-FABP

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Product Notes

The H-FABP (Catalog #AAA584380) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The H-FABP, Human, mAb 67D3 reacts with Reactivity: Human. Cross reactivity: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's H-FABP can be used in a range of immunoassay formats including, but not limited to, Immunoassay (IA), Immunoprecipitation (IP), Western Blot (WB). Application Notes: IP: Biotinylated 67D3 was immobilized on streptavidin beads and added to serum to immunoprecipitate H-FABP (Ref.3). Application Use: For immunohistology and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Researchers should empirically determine the suitability of the H-FABP for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "H-FABP, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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