CD66a (CEACAM1) Recombinant Protein | CD66 recombinant protein
Mouse CD66a Recombinant (CEACAM1)
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Avoid repeated freeze/thaw cycles.
• ceacam1 (CD66a) promotes human monocyte survival via a phosphatidylinositol 3-kinase- and akt-dependent pathway .J. Biol. Chem., Dec 2006; 281: 39179 - 39193.
• neisseria gonorrhoeae kills carcinoembryonic antigen-related cellular adhesion molecule 1 (CD66a) -expressing human b cells and inhibits antibody production .Infect. Immun., Jul 2005; 73: 4171 - 4179.
• significance of the adhesion molecule ceacam1 (CD66a) as a prognostic factor for survival in patients with carcinomas of the lung .AACR Meeting Abstracts, Mar 2004; 2004: 1217.
• CD66a interactions between human melanoma and nk cells: a novel class i mhc-independent inhibitory mechanism of cytotoxicity .J. Immunol., Mar 2002; 168: 2803 - 2810.
NCBI and Uniprot Product Information
Uniprot Description
CEACAM1: carcinoembryonic antigen-related cell adhesion molecule 1. A cell-cell adhesion molecule that directly associates with annexin II. Has tumor suppressor activity in prostate carcinoma. Belongs to the immunoglobulin superfamily and the CEA family. Abundantly expressed in epithelia, vessel endothelia, trophoblasts, platelets and neutrophilic granulocytes. Also present in many cell types of the immune system such as B cells, T cells, NK cells, macrophages and dendritic cells. Five alternatively spliced isoforms have been described. Two isoforms are type I membrane proteins, while three are secreted.
Protein type: Cell adhesion; Immunoglobulin superfamily; Membrane protein, integral; Motility/polarity/chemotaxis
Cellular Component: extracellular space; membrane; brush border membrane; integral to membrane; plasma membrane; external side of plasma membrane
Molecular Function: viral receptor activity; protein binding; protein homodimerization activity; virion binding; protein kinase binding
Biological Process: Peyer's patch development; negative regulation of JNK cascade; entry of virus into host cell; viral reproduction; positive regulation of NFAT protein import into nucleus; positive regulation of JNK cascade; positive regulation of immunoglobulin secretion; calcium-independent cell-cell adhesion; negative regulation of interleukin-2 production; positive regulation of MAP kinase activity; negative regulation of T cell proliferation; negative regulation of cytokine production; calcium-dependent cell-cell adhesion; positive regulation of T cell proliferation; homophilic cell adhesion
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Product Notes
The CD66 ceacam1 (Catalog #AAA553295) is a Recombinant Protein produced from HEk293 Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CD66a (CEACAM1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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