Typical Testing Data/Standard Curve (for reference only)
Mouse Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) ELISA Kit | CEACAM1 elisa kit
Mouse Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: CEA ELISA kit applies the quantitative sandwich enzyme immunoassay technique. The microtiter plate has been pre-coated with a monoclonal antibody specific for CEA. Standards or samples are then added to the microtiter plate wells and CEA if present, will bind to the antibody pre-coated wells. In order to quantitatively determine the amount of CEA present in the sample, a standardized preparation of horseradish peroxidase (HRP)-conjugated polyclonal antibody, specific for CEA are added to each well to "sandwich" the CEA immobilized on the plate. The microtiter plate undergoes incubation, and then the wells are thoroughly washed to remove all unbound components. Next, substrate solutions are added to each well. The enzyme (HRP) and substrate are allowed to react over a short incubation period. Only those wells that contain CEA and enzyme-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The CEA concentration in each sample is interpolated from this standard curve.
NCBI and Uniprot Product Information
Uniprot Description
CEACAM1: carcinoembryonic antigen-related cell adhesion molecule 1. A cell-cell adhesion molecule that directly associates with annexin II. Has tumor suppressor activity in prostate carcinoma. Belongs to the immunoglobulin superfamily and the CEA family. Abundantly expressed in epithelia, vessel endothelia, trophoblasts, platelets and neutrophilic granulocytes. Also present in many cell types of the immune system such as B cells, T cells, NK cells, macrophages and dendritic cells. Five alternatively spliced isoforms have been described. Two isoforms are type I membrane proteins, while three are secreted.
Protein type: Membrane protein, integral; Cell adhesion; Immunoglobulin superfamily; Motility/polarity/chemotaxis
Cellular Component: extracellular space; membrane; brush border membrane; integral to membrane; plasma membrane; external side of plasma membrane
Molecular Function: viral receptor activity; protein binding; protein homodimerization activity; virion binding; protein kinase binding
Biological Process: Peyer's patch development; negative regulation of JNK cascade; entry of virus into host cell; positive regulation of NFAT protein import into nucleus; viral reproduction; positive regulation of JNK cascade; positive regulation of immunoglobulin secretion; calcium-independent cell-cell adhesion; negative regulation of interleukin-2 production; positive regulation of MAP kinase activity; negative regulation of T cell proliferation; negative regulation of cytokine production; calcium-dependent cell-cell adhesion; positive regulation of T cell proliferation; homophilic cell adhesion
Research Articles on CEACAM1
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Product Notes
The Mouse CEACAM1 ceacam1 (Catalog #AAA7215929) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7215929 ELISA Kit recognizes Mouse CEACAM1. It is sometimes possible for the material contained within the vial of "Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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