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Rabbit EHD1 Polyclonal Antibody | anti-EHD1 antibody

EHD1 Antibody BIOTIN-Conjugated

Gene Names
EHD1; PAST; PAST1; H-PAST; HPAST1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Synonyms
EHD1; Polyclonal Antibody; EHD1 Antibody BIOTIN-Conjugated; CDABP0131; EH domain containing 1; FLJ42622; FLJ44618; H PAST; PAST; PAST1; Testilin antibody; anti-EHD1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Form/Format
BIOTIN-Conjugated
Concentration
0.58 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
534
Applicable Applications for anti-EHD1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:500
Immunogen
Synthetic peptide taken wtihin amino acid region 515-565 on human EH-domain containing protein 1.
Expression
testis
Molecular Function
Rab GTPase binding; ATP binding; calcium ion binding
Structure
Homooligomer, and heterooligomer with EHD2, EHD3 and EHD4, ATP-binding is required for heterooligomerization.
Subcellular Location
Cell membrane, Endosome, Membrane
Preparation and Storage
-20 degree C for long term storage
Related Product Information for anti-EHD1 antibody
BIOTIN-Conjugated EH domain-containing protein 1 Antibody
Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Plays a role in myoblast fusion. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
60,627 Da
NCBI Official Full Name
EH domain-containing protein 1
NCBI Official Synonym Full Names
EH domain containing 1
NCBI Official Symbol
EHD1
NCBI Official Synonym Symbols
PAST; PAST1; H-PAST; HPAST1
NCBI Protein Information
EH domain-containing protein 1
UniProt Protein Name
EH domain-containing protein 1
UniProt Gene Name
EHD1
UniProt Synonym Gene Names
hPAST1
UniProt Entry Name
EHD1_HUMAN

NCBI Description

This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]

Uniprot Description

EHD1: Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes.

Protein type: Vesicle; Calcium-binding

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: early endosome membrane; endosome membrane; lipid particle; membrane; plasma membrane; recycling endosome membrane

Molecular Function: ATP binding; calcium ion binding; GTP binding; protein binding; Rab GTPase binding

Biological Process: blood coagulation; cholesterol homeostasis; cilium biogenesis; endocytic recycling; endocytosis; intracellular protein transport; neurite development; protein homooligomerization

Research Articles on EHD1

Similar Products

Product Notes

The EHD1 ehd1 (Catalog #AAA541473) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EHD1 Antibody BIOTIN-Conjugated reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's EHD1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Dot Blot: 1:10,000 ELISA: 1:10,000 Western Blot: 1:500. Researchers should empirically determine the suitability of the EHD1 ehd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EHD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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