MMP2 recombinant protein

MMP2 protein

Cat. Num. AAA537144

• Gene Names: Mmp2; 2-MMP; anon-WO0118547.84; CG1794; dm-2MMP; Dm2-MMP; DmelCG1794; dmmp2; l(2)02353; mmp2; MMP2
• Applications: User optimized
• Purity: > 90% pure
• Synonyms: MMP2; MMP2 protein; MMP 2 protein; Matrix Metalloproteinase 2 Protein; MMP 2; MMP 2 Protein; MMP-2 protein; MMP-2; MMP-2 Protein; MMP2 recombinant protein

• Host: Human
• Purity/Purification: > 90% pure
• Form/Format: 50mM HEPES, 10mM CaCl2, 20% glycerol, with 0.005% BRIJ-35 detergent, pH 7.5.
• Sequence Length: 758

• Applicable Applications for MMP2 recombinant protein: User optimized
• Protein Type: Recombinant
• Biological Significance: 72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis.
• Expression System: CHO cells
• Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
• Preparation and Storage: Aliquot and store at -70 degree C or lower. Avoid repeated freeze/thaw cycles

Related Product Information for MMP2 recombinant protein

Purified recombinant Human MMP2 protein

Product Categories/Family for MMP2 recombinant protein

Proteases; Inhibitors; & Enzymes

NCBI and Uniprot Product Information

• NCBI GI #: 45552531
• NCBI GeneID: 35997
• NCBI Accession #: NP_995788.1
• NCBI GenBank Nucleotide #: NM_206066.2
• UniProt Accession #: Q8MPP3
• Molecular Weight: 89,137 Da
• NCBI Official Full Name: matrix metalloproteinase 2, isoform B
• NCBI Official Synonym Full Names: Matrix metalloproteinase 2
• NCBI Official Symbol: Mmp2
• NCBI Official Synonym Symbols: 2-MMP; anon-WO0118547.84; CG1794; dm-2MMP; Dm2-MMP; DmelCG1794; dmmp2; l(2)02353; mmp2; MMP2
• NCBI Protein Information: CG1794 gene product from transcript CG1794-RB
• UniProt Protein Name: FI21212p1
• Protein Family: Matrix metalloproteinase
• UniProt Gene Name: Mmp2
• UniProt Entry Name: Q8MPP3_DROME

Uniprot Description

Has metalloproteinase activity (PubMed:11967260). Required for larval tissue histolysis during metamorphosis and is involved in pupal head eversion and fusion of the wing imaginal tissue (PubMed:12530966). Required for growth of the dorsal air sac primordium and development of the dorsal air sacs (PubMed:19751719). Promotes embryonic motor axon fasciculation (PubMed:18045838). Cleaves and activates frac to promote motor axon bundling during outgrowth (PubMed:21471368). Promotes the reshaping of adult sensory neuron dendrites from a radial to lattice-like shape which occurs after eclosion by degrading the basement membrane on which the dendrites grow (PubMed:20412776). Involved in inhibition of follicle stem cell proliferation by cleaving Dlp, inhibiting its interaction with wg and preventing Dlp-mediated spreading of wg to follicle stem cells to enhance their proliferation (PubMed:25267296). Plays a role in wound healing (PubMed:22262460). Involved in fat body dissociation which occurs during metamorphosis by degrading basement membrane components, leading to destruction of cell-basement membrane junctions (PubMed:25520167). Required for posterior follicle cell degradation and ovulation (PubMed:25695427).