Western Blot (WB)
(Western blot analysis of LAT (pY255) expression in HEK293T (A); Raw264.7 (B); H9C2 (C) whole cell lysates.)
Rabbit LAT Polyclonal Antibody | anti-LAT antibody
LAT Antibody
Gene Names
LAT; LAT1; pp36; IMD52
Applications
Western Blot
Purity
Immunogen Affinity Chromatography
Synonyms
LAT; Polyclonal Antibody; LAT Antibody; Purified Polyclonal LAT Antibody; Polyclonal LAT antibody; Anti-LAT antibody; Linker for activation of T-cells family member 1 antibody; 36 kDa phospho-tyrosine adapter protein antibody; pp36 antibody; p36-38 antibody; anti-LAT antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of LAT protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
262
Applicable Applications for anti-LAT antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
LAT antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human LAT (pY255) as the immunogen
Cross-Reactivity
Mouse, Rat
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of LAT (pY255) expression in HEK293T (A); Raw264.7 (B); H9C2 (C) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of LAT (pY255) expression in HEK293T (A); Raw264.7 (B); H9C2 (C) whole cell lysates.)
Related Product Information for anti-LAT antibody
LAT is required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells.
Product Categories/Family for anti-LAT antibody
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Research Articles on LAT
Similar Products
Product Notes
The LAT (Catalog #AAA5315991) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's LAT can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the LAT for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LAT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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