Western Blot (WB)
(Western blot analysis of Phogrin expression in HeLa (A); SP2/0 (B); H9C2 (C) whole cell lysates.)
Rabbit Phogrin Polyclonal Antibody | anti-PTPRN2 antibody
Phogrin Antibody
Gene Names
PTPRN2; IAR; ICAAR; PTPRP; IA-2beta; R-PTP-N2
Applications
Western Blot
Purity
Immunogen Affinity Chromatography
Synonyms
Phogrin; Polyclonal Antibody; Phogrin Antibody; Purified Polyclonal Phogrin Antibody; Polyclonal Phogrin antibody; Anti-Phogrin antibody; KIAA0387 antibody; Receptor-type tyrosine-protein phosphatase N2 antibody; R-PTP-N2 antibody; Islet cell autoantigen-related protein antibody; IAR antibody; ICAAR antibody; Phogrin antibody; anti-PTPRN2 antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of Phogrin protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
1015
Applicable Applications for anti-PTPRN2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Phogrin antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Phogrin as the immunogen
Cross-Reactivity
Mouse, Rat
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of Phogrin expression in HeLa (A); SP2/0 (B); H9C2 (C) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of Phogrin expression in HeLa (A); SP2/0 (B); H9C2 (C) whole cell lysates.)
Related Product Information for anti-PTPRN2 antibody
Phogrin is a transmembrane protein expressed in cells with stimulus-coupled peptide hormone secretion, including pancreatic beta cells, in which it is localized to the membrane of insulin-containing dense-core vesicles.
Product Categories/Family for anti-PTPRN2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
phogrin
NCBI Official Synonym Full Names
protein tyrosine phosphatase receptor type N2
NCBI Official Symbol
PTPRN2
NCBI Official Synonym Symbols
IAR; ICAAR; PTPRP; IA-2beta; R-PTP-N2
NCBI Protein Information
receptor-type tyrosine-protein phosphatase N2
Protein Family
NCBI Description
This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Research Articles on PTPRN2
Similar Products
Product Notes
The PTPRN2 (Catalog #AAA5314915) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Phogrin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the PTPRN2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Phogrin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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