Rabbit BCL2 Polyclonal Antibody | anti-BCL2 antibody

BCL2 Antibody (Thr56)

Cat. Num. AAA5313512

• Gene Names: BCL2; Bcl-2; PPP1R50
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity Chromatography
• Synonyms: BCL2; Polyclonal Antibody; BCL2 Antibody (Thr56); Rabbit Polyclonal BCL2 Antibody (Thr56); Polyclonal BCL2 antibody; Anti-BCL2 antibody; Apoptosis regulator Bcl-2 antibody; B-cell CLL/lymphoma 2 antibody; Bcl-2 antibody; BCL2 antibody; anti-BCL2 antibody

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: BCL2 antibody (Thr56) detects endogenous levels of BCL2 only when phosphorylated at threonine 56
• Purity/Purification: Affinity Chromatography
• Form/Format: Supplied in PBS buffer (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 195

• Applicable Applications for anti-BCL2 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:1000; IHC: 1:50-1:100
• Immunogen: BCL2 antibody was raised in Rabbit using a synthesized phosphopeptide derived from human BCL2 around the phosphorylation site of threonine 56 (G-H-TP-P-H) as the immunogen.
• Preparation and Storage: Store at -20 degree C in small aliquots. Avoid repeat freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts from MDA435 cells treated with sorbtiol (0.4M, 30min) using BCL-2 (phospho-Thr56) antibody)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BCL2 antibody (Thr56))

Related Product Information for anti-BCL2 antibody

BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes.

Product Categories/Family for anti-BCL2 antibody

Cell Cycle & Cell Death

NCBI and Uniprot Product Information

• NCBI GI #: 1111819160
• NCBI GeneID: 596
• NCBI Official Full Name: BCL2, partial
• NCBI Official Synonym Full Names: BCL2 apoptosis regulator
• NCBI Official Symbol: BCL2
• NCBI Official Synonym Symbols: Bcl-2; PPP1R50
• NCBI Protein Information: apoptosis regulator Bcl-2
• Protein Family: Bcl2-associated agonist of cell death

NCBI Description

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]