Immunohistochemistry (IHC)
(Immunohistochemical staining of formalin-fixed paraffin-embedded fetal spleen showing cytoplasmic staining with anti-ANXA3 antibody at a dilution of 1/100)
Rabbit ANXA3 Polyclonal Antibody | anti-ANXA3 antibody
ANXA3 Antibody
WB: 1:1,000-1:2,000
IHC: 1:100-1:500
Immunohistochemistry (IHC)
(Immunohistochemical staining of formalin-fixed paraffin-embedded fetal spleen showing cytoplasmic staining with anti-ANXA3 antibody at a dilution of 1/100)
Immunohistochemistry (IHC)
(Immunohistochemical staining of formalin-fixed paraffin-embedded fetal spleen showing cytoplasmic staining with anti-ANXA3 antibody at a dilution of 1/100)
Western Blot (WB)
(Western Blot analysis of K562 cell Lysate with anti-ANXA3 antibody)
Western Blot (WB)
(Western Blot analysis of K562 cell Lysate with anti-ANXA3 antibody)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. [provided by RefSeq, Jul 2008]
Uniprot Description
ANXA3: a calcium/phospholipid-binding protein and inhibitor of phospholipase A2, Possesses anti-coagulant properties. Cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.
Protein type: Calcium-binding
Chromosomal Location of Human Ortholog: 4q21.21
Cellular Component: specific granule; phagocytic vesicle membrane; membrane; cytoplasm; plasma membrane
Molecular Function: calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity; calcium ion binding; calcium-dependent protein binding
Biological Process: positive regulation of angiogenesis; negative regulation of catalytic activity; neutrophil degranulation; defense response to bacterium; positive regulation of transcription factor activity; phagocytosis
Research Articles on ANXA3
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Product Notes
The ANXA3 anxa3 (Catalog #AAA5313396) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ANXA3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-1:80,000 WB: 1:1,000-1:2,000 IHC: 1:100-1:500. Researchers should empirically determine the suitability of the ANXA3 anxa3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ANXA3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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