Western Blot (WB)
(Lane 1: Recombinant Human IL-1beta Protein 20ng, Lane 2: Recombinant Human IL-1beta Protein 10ng, Lane 3: MK(55KD))
Rabbit IL1b Polyclonal Antibody | anti-IL1b antibody
IL1b Antibody
Gene Names
IL1B; IL-1; IL1F2; IL1beta; IL1-BETA
Applications
Western Blot
Purity
Affinity Chromatography
Synonyms
IL1b; Polyclonal Antibody; IL1b Antibody; Affinity Purified Goat Polyclonal IL1b Antibody; Polyclonal IL1b antibody; Anti-IL1b antibody; ILb 1; Interlekin 1 beta antibody; ILb-1 antibody; IL-1b antibody; IL1 beta antibody; ILb-1; ILb 1 antibody; anti-IL1b antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Lyophilized Form
Sequence Length
269
Applicable Applications for anti-IL1b antibody
Western Blot (WB)
Immunogen
IL1b antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human IL1B as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Lane 1: Recombinant Human IL-1beta Protein 20ng, Lane 2: Recombinant Human IL-1beta Protein 10ng, Lane 3: MK(55KD))
Western Blot (WB)
(Lane 1: Recombinant Human IL-1beta Protein 20ng, Lane 2: Recombinant Human IL-1beta Protein 10ng, Lane 3: MK(55KD))
Related Product Information for anti-IL1b antibody
IL1 is a name that designates two pleiotropic cytokines, IL1 alpha (IL1F1) and IL1Beta (IL1F2), which are the products of distinct genes. IL1 alpha and IL1Beta are structurally related polypeptides that share approximately 21% amino acid (aa) identity in human. Both proteins are produced by a wide variety of cells in response to inflammatory agents, infections, or microbial endotoxins. While IL1 alpha and IL1Beta are regulated independently, they bind to the same receptor and exert identical biological effects. IL1 RI binds directly to IL1 alpha or IL1Beta and then associates with IL1 R accessory protein (IL1 R3/IL1 R AcP) to form a highaffinity receptor complex that is competent for signal transduction. IL1 RII has high affinity for IL1Beta but functions as a decoy receptor and negative regulator of IL1Beta activity.
Product Categories/Family for anti-IL1b antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
IL1B, partial
NCBI Official Synonym Full Names
interleukin 1 beta
NCBI Official Symbol
IL1B
NCBI Official Synonym Symbols
IL-1; IL1F2; IL1beta; IL1-BETA
NCBI Protein Information
interleukin-1 beta
Protein Family
NCBI Description
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
Research Articles on IL1b
Similar Products
Product Notes
The IL1b (Catalog #AAA5312674) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IL1b can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the IL1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL1b, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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