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Western Blot (WB) (Lane 1: Rat Cardiac Muscle Tissue Lysate; Lane 2: Rat Brain Tissue Lysate; Lane 3: Rat TesticleTissue Lysate; Lane 4: Rat Placenta Tissue Lysate; Lane 5: MCF-7 Cell Lysate; Lane 6: Hela Cell Lysate; Lane 7: CEM Cell Lysate; Lane 8: SMMC Cell Lysate; Lane 9: Colo320 Cell Lysate)

Rabbit API5 Polyclonal Antibody | anti-API5 antibody

API5 Antibody

Applications
Western Blot, Immunohistochemistry, Immunocytochemistry
Purity
Affinity Chromatography
Synonyms
API5; Polyclonal Antibody; API5 Antibody; Affinity Purified Rabbit Polyclonal API5 Antibody; Polyclonal API5 antibody; Anti-API5 antibody; API-5; API 5; API 5 antibody; Apoptosis inhibitor 5 antibody; API-5 antibody; anti-API5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Lyophilized Form
Sequence Length
524
Applicable Applications for anti-API5 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC)
Immunogen
API5 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human API5, different from the related Rabbit sequence by one amino acid, as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.

Western Blot (WB)

(Lane 1: Rat Cardiac Muscle Tissue Lysate; Lane 2: Rat Brain Tissue Lysate; Lane 3: Rat TesticleTissue Lysate; Lane 4: Rat Placenta Tissue Lysate; Lane 5: MCF-7 Cell Lysate; Lane 6: Hela Cell Lysate; Lane 7: CEM Cell Lysate; Lane 8: SMMC Cell Lysate; Lane 9: Colo320 Cell Lysate)

Western Blot (WB) (Lane 1: Rat Cardiac Muscle Tissue Lysate; Lane 2: Rat Brain Tissue Lysate; Lane 3: Rat TesticleTissue Lysate; Lane 4: Rat Placenta Tissue Lysate; Lane 5: MCF-7 Cell Lysate; Lane 6: Hela Cell Lysate; Lane 7: CEM Cell Lysate; Lane 8: SMMC Cell Lysate; Lane 9: Colo320 Cell Lysate)
Related Product Information for anti-API5 antibody
Many growth factors and cytokines act as cellular survival factors by preventing programmed cell death (apoptosis). Apoptosis inhibitor 5 (API5) is an antiapoptotic factor which may have a role in protein assembly. It is a critical determinant of E2F1-induced apoptosis, acting downstream of E2F to suppress E2F-dependent apoptosis without generally blocking E2F-dependent transcription.
Product Categories/Family for anti-API5 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
apoptosis inhibitor 5 isoform a
UniProt Protein Name
Apoptosis inhibitor 5
Protein Family
UniProt Gene Name
API5
UniProt Synonym Gene Names
API-5; AAC-11; FIF
UniProt Entry Name
API5_HUMAN

Uniprot Description

API5: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Belongs to the API5 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; RNA-binding

Chromosomal Location of Human Ortholog: 11p11.2

Cellular Component: nucleoplasm; spliceosome; membrane; cytoplasm; nucleus

Molecular Function: protein binding; fibroblast growth factor binding

Biological Process: apoptosis; negative regulation of apoptosis

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Product Notes

The API5 api5 (Catalog #AAA5312529) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's API5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the API5 api5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "API5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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