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Rat anti-Murine CD205 Monoclonal Antibody | anti-CD205 antibody

CD205 antibody (FITC)

Reactivity
Murine
Applications
Flow Cytometry, Functional Assay
Synonyms
CD205; Monoclonal Antibody; CD205 antibody (FITC); Monoclonal CD205; Anti-CD205; CD 205; DEC205; CD-205; DEC-205; anti-CD205 antibody
Ordering
For Research Use Only!
Host
Rat
Reactivity
Murine
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
NLDC-145
Specificity
Murine
Form/Format
PBS, pH 7.2, with 10mg/ml BSA and 0.09% NaN3.
Concentration
0.2 mg/ml (varies by lot)
Sequence Length
1723
Applicable Applications for anti-CD205 antibody
Flow Cytometry (FC/FACS)
Biological Significance
CD205 is expressed at high levels by dendritic cells and thymic epithelial cells. It is an integral membrane glycoprotein with an apparent mass of 205 kDa, also known as DEC-205. DEC-205 is apparently a receptor involved in antigen-processing by dendritic cells.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Tag/Conjugate
FITC
Immunogen
CD205 antibody (FITC) was raised in rat using mouse lymph node tissue as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-CD205 antibody
Rat monoclonal CD205 antibody (FITC)
Product Categories/Family for anti-CD205 antibody

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
197,352 Da
NCBI Official Full Name
DEC205
UniProt Protein Name
Lymphocyte antigen 75
UniProt Gene Name
Ly75
UniProt Synonym Gene Names
Cd205; Ly-75
UniProt Entry Name
LY75_MOUSE

Uniprot Description

LY75: Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment. Causes reduced proliferation of B-lymphocytes. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: membrane; integral to membrane; external side of plasma membrane

Molecular Function: carbohydrate binding

Biological Process: endocytosis

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Product Notes

The CD205 ly75 (Catalog #AAA530846) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The CD205 antibody (FITC) reacts with Murine and may cross-react with other species as described in the data sheet. AAA Biotech's CD205 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the CD205 ly75 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD205, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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