Rat Substance P Monoclonal Antibody | anti-Tac1 antibody
Substance P antibody
Gene Names
Tac1; TAC; PPTA3; Ppt5fl; RATPPTA3
Reactivity
To be determined by end-user
Applications
Immunohistochemistry
Synonyms
Substance P; Monoclonal Antibody; Substance P antibody; Monoclonal Substance P; Anti-Substance P; anti-Tac1 antibody
Host
Rat
Reactivity
To be determined by end-user
Clonality
Monoclonal
Isotype
IgGa
Clone Number
M09205
Form/Format
Supplied as a lyophilized powder. Reconstitute with 0.5 ml of distilled water.
Sequence Length
97
Applicable Applications for anti-Tac1 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:200-1:500
Biological Significance
Substance P (SP) is a neuropeptide: an undecapeptide that functions as a neurotransmitter and as a neuromodulator. It belongs to the tachykinin neuropeptide family. Substance P and its closely related neuropeptide neurokinin A (NKA) are produced from a polyprotein precursor after differential splicing of the preprotachykinin A gene.
Immunogen
Substance P antibody was raised in rat using substance-P-BSA as the immunogen.
Preparation and Storage
Store at 4 degree C.
Related Product Information for anti-Tac1 antibody
Rat monoclonal Substance P antibody
Product Categories/Family for anti-Tac1 antibody
References
Effects of extended sidestream smoke exposure on components of the C-fiber axon reflex; Jesse P. Joad, Krishna P. Avadhanam, Katherine C. Watt, Kayleen S. Kott, John M. Bric, Kent E. Pinkerton (Toxicology: Volume: 112 Issue: 3 Page: 195-203 DOI: 10.1016/0300-483X(96)03403-8)
Endocytosis and recycling of neurokinin 1 receptors in enteric neurons; E.F Grady, P.D Gamp, E Jones, P Baluk, D.M McDonald, D.G Payan, N.W Bunnett (Neuroscience: Volume: 75 Issue: 4 Page: 12391254 DOI: 10.1016/0306-4522(96)00357-0)
Perinatal environmental tobacco smoke exposure alters the immune response and airway innervation in infant primates; Mang Yu, Xiaomu Zheng, Janice Peake, Jesse P. Joad, Kent E. Pinkerton (Journal of Allergy and Clinical Immunology: Volume: 122 Issue: 3 Page: 640-647.e1 DOI: 10.1016/j.jaci.2008.04.038)
Labeling of calcitonin gene-related peptide and substance P increases in subnucleus caudalis of rabbit during maxillary sinusitis; A.K Rochea, Ioannis G Koutlasb, K.C Kajander (Brain Research: Volume: 791 Issue: 1-2 Page: 283-289 DOI: 10.1016/S0006-8993(97)01556-4)
Identification of the cholinergic neurons in Guinea-pig sphincter of Oddi ganglia; Erin K Talmage, Kirk Hillsley, Audra L Kennedy, Gary M Mawe (Journal of the Autonomic Nervous System: Volume: 64 Issue: 1 Page: 12-18 DOI: 10.1016/S0165-1838(97)00009-X)
Endocytosis and recycling of neurokinin 1 receptors in enteric neurons; E.F Grady, P.D Gamp, E Jones, P Baluk, D.M McDonald, D.G Payan, N.W Bunnett (Neuroscience: Volume: 75 Issue: 4 Page: 12391254 DOI: 10.1016/0306-4522(96)00357-0)
Perinatal environmental tobacco smoke exposure alters the immune response and airway innervation in infant primates; Mang Yu, Xiaomu Zheng, Janice Peake, Jesse P. Joad, Kent E. Pinkerton (Journal of Allergy and Clinical Immunology: Volume: 122 Issue: 3 Page: 640-647.e1 DOI: 10.1016/j.jaci.2008.04.038)
Labeling of calcitonin gene-related peptide and substance P increases in subnucleus caudalis of rabbit during maxillary sinusitis; A.K Rochea, Ioannis G Koutlasb, K.C Kajander (Brain Research: Volume: 791 Issue: 1-2 Page: 283-289 DOI: 10.1016/S0006-8993(97)01556-4)
Identification of the cholinergic neurons in Guinea-pig sphincter of Oddi ganglia; Erin K Talmage, Kirk Hillsley, Audra L Kennedy, Gary M Mawe (Journal of the Autonomic Nervous System: Volume: 64 Issue: 1 Page: 12-18 DOI: 10.1016/S0165-1838(97)00009-X)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
11,374 Da
NCBI Official Full Name
substance P
NCBI Official Synonym Full Names
tachykinin, precursor 1
NCBI Official Symbol
Tac1
NCBI Official Synonym Symbols
TAC; PPTA3; Ppt5fl; RATPPTA3
NCBI Protein Information
protachykinin-1
UniProt Protein Name
Protachykinin-1
Protein Family
UniProt Gene Name
Tac1
UniProt Synonym Gene Names
Nka; Nkna; Tac2; NKA; NPK
UniProt Entry Name
TKN1_RAT
NCBI Description
encodes neuropeptides substance P, neurokinin A, neuropeptide K, and neuropeptide gamma [RGD, Feb 2006]
Uniprot Description
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
Research Articles on Tac1
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Product Notes
The Tac1 tac1 (Catalog #AAA530819) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Substance P antibody reacts with To be determined by end-user and may cross-react with other species as described in the data sheet. AAA Biotech's Substance P can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:200-1:500. Researchers should empirically determine the suitability of the Tac1 tac1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Substance P, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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