Testing Data
Mouse anti-Rat C3a Receptor Monoclonal Antibody
Anti-Rat C3a Receptor, Purified (Clone 74) (mouse IgG1)
Reactivity
Rat
Applications
Immunohistochemistry, Flow Cytometry, Functional Assay
Synonyms
C3a Receptor; Monoclonal Antibody; Anti-Rat C3a Receptor; Purified (Clone 74) (mouse IgG1); Purified Anti-Rat C3a Receptor (C3aR) Monoclonal Antibody; anti-C3a Receptor antibody
Host
Mouse
Reactivity
Rat
Clonality
Monoclonal
Isotype
Mouse IgG1
Clone Number
74
Specificity
C3a receptor (Rat C3aR)
Form/Format
Purified (Purified Ig buffered in PBS and 0.02% NaN3. (Purified from ascitic fluid via Protein G Chromatography))
Concentration
Antibody Concentration: 1.0 mg/ml (varies by lot)
Applicable Applications for anti-C3a Receptor antibody
Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Immunogen
RBL-2H3 transfectants expressing rat C3aR
Donor
BALB/c
Fusion Partner
X63-Ag8.653
Presentation
250ug purified Ig buffered in PBS and 0.02% NaN3
Preparation and Storage
Store at + 4 degree C. For long term storage, aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles
Testing Data
Testing Data
Related Product Information for anti-C3a Receptor antibody
C3aR binds to anaphylotoxin C3a which, among other things, is involved in mast cell degranulation and recruitment of immune cells to the site of inflammation. Activation of the complement cascade produces various fragments, including C3a and C5a. C3aR is characterized by seven transmembrane domains including a large extracellular loop which is coupled to a Gi protein. C3aR expression is detected on glial cells, neurons and cells belonging to the mononuclear phagocyte system. C3aR expression was shown to moderately increase after LPS stimulation. rat C3a receptor antibody detects a recombinant peptide corresponding to amino acids 161-321 of the large extracellular loop structure, which shares 34% homology with mouse and human. Deduced amino acid sequences of human/rat C3aR is 58.5% and 90.7% with rat/mouse. This clone is suitable for use in flow cytometry and frozen tissue sections.
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Product Notes
The C3a Receptor (Catalog #AAA520015) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Rat C3a Receptor, Purified (Clone 74) (mouse IgG1) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's C3a Receptor can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the C3a Receptor for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C3a Receptor, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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