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Western Blot (WB) (Western blot analysis using CTNNBL1 mAb against human CTNNBL1 (AA)

Mouse anti-Human CTNNBL1 Monoclonal Antibody | anti-CTNNBL1 antibody

Anti-CTNNBL1 Mouse mAb

Gene Names
CTNNBL1; NAP; P14L; PP8304; C20orf33; dJ633O20.1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry, Functional Assay
Synonyms
CTNNBL1; Monoclonal Antibody; Anti-CTNNBL1 Mouse mAb; NAP; P14L; PP8304; C20orf33; dJ633O20.1; anti-CTNNBL1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1E4F5
Form/Format
Purified antibody in PBS with 0.05% sodium azide.
Sequence Length
311
Applicable Applications for anti-CTNNBL1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
Immunogen
Purified recombinant fragment of human CTNNBL1 (AA: 390-557) expressed in E Coli.

Western Blot (WB)

(Western blot analysis using CTNNBL1 mAb against human CTNNBL1 (AA)

Western Blot (WB) (Western blot analysis using CTNNBL1 mAb against human CTNNBL1 (AA)

Western Blot (WB)

(Western blot analysis using CTNNBL1 mAb against HEK293 (1) and CTNNBL1 (AA)

Western Blot (WB) (Western blot analysis using CTNNBL1 mAb against HEK293 (1) and CTNNBL1 (AA)

Western Blot (WB)

(Western blot analysis using CTNNBL1 mouse mAb against Hela (1), Jurkat (2), HEK293 (3), A431 (4), HepG2 (5), RAJI (6) cell lysate.)

Western Blot (WB) (Western blot analysis using CTNNBL1 mouse mAb against Hela (1), Jurkat (2), HEK293 (3), A431 (4), HepG2 (5), RAJI (6) cell lysate.)

Immunofluorescence (IF)

(Immunofluorescence analysis of MCF-7 cells using CTNNBL1 mouse mAb (green). Blue)

Immunofluorescence (IF) (Immunofluorescence analysis of MCF-7 cells using CTNNBL1 mouse mAb (green). Blue)

Flow Cytometry (FC/FACS)

(Flow cytometric analysis of Hela cells using CTNNBL1 mouse mAb (green) and negative control (red).)

Flow Cytometry (FC/FACS) (Flow cytometric analysis of Hela cells using CTNNBL1 mouse mAb (green) and negative control (red).)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded colon cancer tissues using CTNNBL1 mouse mAb with DAB staining.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded colon cancer tissues using CTNNBL1 mouse mAb with DAB staining.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using CTNNBL1 mouse mAb with DAB staining.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using CTNNBL1 mouse mAb with DAB staining.)
Related Product Information for anti-CTNNBL1 antibody
Entrez Summary: The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
65.2
NCBI Official Full Name
CTNNBL1, partial
NCBI Official Synonym Full Names
catenin beta like 1
NCBI Official Symbol
CTNNBL1
NCBI Official Synonym Symbols
NAP; P14L; PP8304; C20orf33; dJ633O20.1
NCBI Protein Information
beta-catenin-like protein 1
UniProt Protein Name
Beta-catenin-like protein 1
Protein Family
UniProt Gene Name
CTNNBL1
UniProt Synonym Gene Names
C20orf33; NAP

NCBI Description

The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013]

Uniprot Description

CTNNBL1: Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA splicing; Spliceosome

Chromosomal Location of Human Ortholog: 20q11.23

Cellular Component: membrane; nucleoplasm; nucleus; spliceosome

Molecular Function: enzyme binding; protein binding

Biological Process: nuclear mRNA splicing, via spliceosome; positive regulation of apoptosis; somatic diversification of immunoglobulins

Research Articles on CTNNBL1

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Product Notes

The CTNNBL1 ctnnbl1 (Catalog #AAA476562) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-CTNNBL1 Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CTNNBL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the CTNNBL1 ctnnbl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CTNNBL1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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