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Western Blot (WB) (Western Blot analysis of INSM1 in Mouse lung tissue and Mouse thymus tissue lysates in order using INSM1 Rabbit pAb at dilution 1/400)

Rabbit anti-Human, Mouse INSM1 Polyclonal Antibody | anti-INSM1 antibody

INSM1 Rabbit pAb

Gene Names
INSM1; IA1; IA-1
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Affinity purified
Synonyms
INSM1; Polyclonal Antibody; INSM1 Rabbit pAb; INSM transcriptional repressor 1; IA1; IA-1; anti-INSM1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
1.32mg/ml (varies by lot)
Applicable Applications for anti-INSM1 antibody
Western Blot (WB)
Application Notes
WB: 1:200-1:1000
Immunogen
Synthetic peptide of human INSM1
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of INSM1 in Mouse lung tissue and Mouse thymus tissue lysates in order using INSM1 Rabbit pAb at dilution 1/400)

Western Blot (WB) (Western Blot analysis of INSM1 in Mouse lung tissue and Mouse thymus tissue lysates in order using INSM1 Rabbit pAb at dilution 1/400)
Related Product Information for anti-INSM1 antibody
Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
52,923 Da
NCBI Official Full Name
insulinoma-associated protein 1
NCBI Official Synonym Full Names
insulinoma-associated 1
NCBI Official Symbol
INSM1
NCBI Official Synonym Symbols
IA1; IA-1
NCBI Protein Information
insulinoma-associated protein 1; zinc finger protein IA-1
UniProt Protein Name
Insulinoma-associated protein 1
UniProt Gene Name
INSM1
UniProt Synonym Gene Names
IA1
UniProt Entry Name
INSM1_HUMAN

NCBI Description

Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors. [provided by RefSeq, Jul 2008]

Uniprot Description

INSM1: May be associated with the transformation of neuroendocrine cells.

Protein type: C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 20p11.2

Cellular Component: nucleoplasm; transcriptional repressor complex; nucleus

Molecular Function: cyclin binding; chromatin DNA binding; histone deacetylase binding; metal ion binding; transcription factor activity

Biological Process: norepinephrine biosynthetic process; negative regulation of cell proliferation; transcription, DNA-dependent; negative regulation of protein amino acid phosphorylation; regulation of gene expression; regulation of protein complex assembly; negative regulation of transcription from RNA polymerase II promoter; cell cycle; positive regulation of cell differentiation; endocrine pancreas development

Research Articles on INSM1

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Product Notes

The INSM1 insm1 (Catalog #AAA4760965) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The INSM1 Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's INSM1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:200-1:1000. Researchers should empirically determine the suitability of the INSM1 insm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "INSM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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