Immunohistochemistry (IHC)
(Human Heart)
Rabbit INSM1 Polyclonal Antibody | anti-INSM1 antibody
INSM1 antibody - middle region
Immunohistochemistry (IHC)
(Human Heart)
Immunohistochemistry (IHC)
(Human Heart)
Western Blot (WB)
(WB Suggested Anti-INSM1 Antibody Titration: 1.25ug/mlPositive Control: Human Cerebellum)
Western Blot (WB)
(WB Suggested Anti-INSM1 Antibody Titration: 1.25ug/mlPositive Control: Human Cerebellum)
Target Description: Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors.
NCBI and Uniprot Product Information
NCBI Description
Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors. [provided by RefSeq, Jul 2008]
Uniprot Description
INSM1: May be associated with the transformation of neuroendocrine cells.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 20p11.2
Cellular Component: nucleoplasm; transcriptional repressor complex; nucleus
Molecular Function: cyclin binding; chromatin DNA binding; histone deacetylase binding; metal ion binding; transcription factor activity
Biological Process: norepinephrine biosynthetic process; negative regulation of cell proliferation; transcription, DNA-dependent; negative regulation of protein amino acid phosphorylation; regulation of gene expression; regulation of protein complex assembly; negative regulation of transcription from RNA polymerase II promoter; cell cycle; positive regulation of cell differentiation; endocrine pancreas development
Research Articles on INSM1
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Product Notes
The INSM1 insm1 (Catalog #AAA3200691) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The INSM1 antibody - middle region reacts with Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's INSM1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the INSM1 insm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: PAAALRPPGK RPPPPTAAEP PAKAVKAPGA KKPKAIRKLH FEDEVTTSPV. It is sometimes possible for the material contained within the vial of "INSM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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