Immunofluorescence (IF)
(Confocal immunofluorescence analysis of Hela (A), A431 (B) and THP-1 (C) cells using RTN3 mouse mAb (green). Blue)
Mouse anti-Human RTN3 Monoclonal Antibody | anti-RTN3 antibody
Anti-RTN3 Mouse mAb
Gene Names
Rtn3; RTN3-A1
Reactivity
Human
Applications
Immunocytochemistry
Synonyms
RTN3; Monoclonal Antibody; Anti-RTN3 Mouse mAb; HAP; ASYIP; NSPL2; NSPLII; RTN3-A1; anti-RTN3 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
1E11
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
256
Applicable Applications for anti-RTN3 antibody
Immunocytochemistry (ICC)
Immunogen
Purified recombinant fragment of RTN3 expressed in E Coli.
Immunofluorescence (IF)
(Confocal immunofluorescence analysis of Hela (A), A431 (B) and THP-1 (C) cells using RTN3 mouse mAb (green). Blue)
Immunofluorescence (IF)
(Confocal immunofluorescence analysis of Hela (A), A431 (B) and THP-1 (C) cells using RTN3 mouse mAb (green). Blue)
Related Product Information for anti-RTN3 antibody
Entrez Summary: RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
113
NCBI Official Full Name
reticulon-3 isoform 6
NCBI Official Synonym Full Names
reticulon 3
NCBI Official Symbol
Rtn3
NCBI Official Synonym Symbols
RTN3-A1
NCBI Protein Information
reticulon-3
UniProt Protein Name
Reticulon-3
Protein Family
UniProt Gene Name
Rtn3
Uniprot Description
RTN3: May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 19|19 A
Cellular Component: endomembrane system; endoplasmic reticulum; endoplasmic reticulum membrane
Molecular Function: protein binding
Research Articles on RTN3
Similar Products
Product Notes
The RTN3 rtn3 (Catalog #AAA475939) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-RTN3 Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RTN3 can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the RTN3 rtn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RTN3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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