Western Blot (WB)
(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: Human gastric carcinoma tissue lysate, Primary antibody: 163296(BTBD6 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes)
Rabbit anti-Human BTB/POZ domain containing protein 6 Polyclonal Antibody | anti-BTB/POZ antibody
BTB/POZ domain containing protein 6 Rabbit pAb
Gene Names
BTBD6; BDPL
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
BTB/POZ domain containing protein 6; Polyclonal Antibody; BTB/POZ domain containing protein 6 Rabbit pAb; anti-BTB/POZ antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity purified
Form/Format
-20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Applicable Applications for anti-BTB/POZ antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:200-1:1000
Immunogen
Synthetic peptide of human BTBD6
Conjugation
Unconjugated
Molecular Function
BTBD6 (BTB/POZ domain-containing protein 6), also known as BDPL or lens BTB domain protein, is a 410 amino acid protein that contains one BTB/POZ domain and is specifically expressed in the lens. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD6 may play a role in transcription regulation in the lens.
Modification
Unmodified
Cell Position
Cytoplasm
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.
Western Blot (WB)
(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: Human gastric carcinoma tissue lysate, Primary antibody: 163296(BTBD6 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes)
Western Blot (WB)
(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: Human gastric carcinoma tissue lysate, Primary antibody: 163296(BTBD6 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes)
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 163296(BTBD6 Antibody) at dilution 1/25. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 163296(BTBD6 Antibody) at dilution 1/25. (Original magnification: ×200))
Product Categories/Family for anti-BTB/POZ antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,925 Da
NCBI Official Full Name
BTB/POZ domain-containing protein 6
NCBI Official Synonym Full Names
BTB (POZ) domain containing 6
NCBI Official Symbol
BTBD6
NCBI Official Synonym Symbols
BDPL
NCBI Protein Information
BTB/POZ domain-containing protein 6; BTB domain protein BDPL; glucocorticoid receptor AF-1 coactivator-1; lens BTB domain protein
UniProt Protein Name
BTB/POZ domain-containing protein 6
UniProt Gene Name
BTBD6
UniProt Synonym Gene Names
BDPL
UniProt Entry Name
BTBD6_HUMAN
Uniprot Description
BTBD6: Adapter protein for the CUL3 E3 ubiquitin-protein ligase complex. Involved in late neuronal development and muscle formation. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 14q32
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Product Notes
The BTB/POZ btbd6 (Catalog #AAA4754989) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BTB/POZ domain containing protein 6 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BTB/POZ domain containing protein 6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:200-1:1000. Researchers should empirically determine the suitability of the BTB/POZ btbd6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BTB/POZ domain containing protein 6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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