Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 160185(CLEC5A Antibody) at dilution 1/20. (Original magnification: ×200))
Rabbit anti-Human CLEC5A Polyclonal Antibody | anti-CLEC5A antibody
CLEC5A Rabbit pAb
Gene Names
CLEC5A; MDL1; MDL-1; CLECSF5
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Affinity purified
Synonyms
CLEC5A; Polyclonal Antibody; CLEC5A Rabbit pAb; C-type lectin domain family 5; member A; MDL1; MDL-1; CLECSF5; anti-CLEC5A antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Highly expressed in bone marrow with lower levels in synovium, lung and bronchus (PubMed:20212065). Expressed in peripheral blood monocytes and in the monocyte/macrophage cell lines U-937 and Mono-Mac-6, but not in cell lines of other origins (PubMed:10449773). Expression is down-regulated when monocytes differentiate into dendritic cells (PubMed:10449773).
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Applicable Applications for anti-CLEC5A antibody
ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
ELISA: 1:2000-1:5000
IHC: 1:50-1:200
IHC: 1:50-1:200
Immunogen
Synthetic peptide of human CLEC5A
Conjugation
Unconjugated
Molecular Function
Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP (PubMed:10449773). Regulates inflammatory responses.
Modification
Unmodified
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 160185(CLEC5A Antibody) at dilution 1/20. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 160185(CLEC5A Antibody) at dilution 1/20. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 160185(CLEC5A Antibody) at dilution 1/20.(Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 160185(CLEC5A Antibody) at dilution 1/20.(Original magnification: ×200))
Related Product Information for anti-CLEC5A antibody
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined.
Product Categories/Family for anti-CLEC5A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
188
NCBI Official Full Name
C-type lectin domain family 5 member A
NCBI Official Synonym Full Names
C-type lectin domain family 5, member A
NCBI Official Symbol
CLEC5A
NCBI Official Synonym Symbols
MDL1; MDL-1; CLECSF5
NCBI Protein Information
C-type lectin domain family 5 member A; C-type lectin superfamily member 5; myeloid DAP12-associating lectin 1; myeloid DAP12-associating lectin-1; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5
UniProt Protein Name
C-type lectin domain family 5 member A
Protein Family
UniProt Gene Name
CLEC5A
UniProt Synonym Gene Names
CLECSF5; MDL1; MDL-1
UniProt Entry Name
CLC5A_HUMAN
Similar Products
Product Notes
The CLEC5A clec5a (Catalog #AAA4754658) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLEC5A Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLEC5A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P). ELISA: 1:2000-1:5000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the CLEC5A clec5a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLEC5A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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