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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human colon, using p16 ARC Antibody.)

Rabbit p16 ARC Polyclonal Antibody | anti-ARC16 antibody

Anti-p16 ARC Rabbit pAb

Gene Names
ARPC5; ARC16; p16-Arc; dJ127C7.3
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Flow Cytometry, Functional Assay
Purity
Affinity Chromatography
Synonyms
p16 ARC; Polyclonal Antibody; Anti-p16 ARC Rabbit pAb; p16 Arc; ARPC5; Arp2/3 protein complex subunit p16; anti-ARC16 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
p16 ARC Antibody detects endogenous levels of total p16 ARC
Purity/Purification
Affinity Chromatography
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
Sequence Length
154
Applicable Applications for anti-ARC16 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:100
ICC/IF: 1:50-1:100
IP: 1:50
FC/FACS 1:50
Immunogen
A synthesized peptide derived from human p16 ARC
Subcellular Location
Cell projection, Cytoplasm, Cytoskeleton
Preparation and Storage
Store at 4 degree C short term. Store at -20 degree C long term. Avoid freeze/thaw cycle.

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human colon, using p16 ARC Antibody.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human colon, using p16 ARC Antibody.)
Related Product Information for anti-ARC16 antibody
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16 kDa
NCBI Official Full Name
actin-related protein 2/3 complex subunit 5 isoform 2
NCBI Official Synonym Full Names
actin related protein 2/3 complex subunit 5
NCBI Official Symbol
ARPC5
NCBI Official Synonym Symbols
ARC16; p16-Arc; dJ127C7.3
NCBI Protein Information
actin-related protein 2/3 complex subunit 5
UniProt Protein Name
Actin-related protein 2/3 complex subunit 5
UniProt Gene Name
ARPC5
UniProt Synonym Gene Names
ARC16; p16-ARC
UniProt Entry Name
ARPC5_HUMAN

NCBI Description

This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Uniprot Description

ARPC5: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Belongs to the ARPC5 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 1q25.3

Cellular Component: Arp2/3 protein complex; focal adhesion; cell projection; cytoplasm; cytosol; actin cytoskeleton

Molecular Function: actin filament binding; protein binding; structural constituent of cytoskeleton

Biological Process: axon guidance; ephrin receptor signaling pathway; innate immune response; actin cytoskeleton organization and biogenesis; cell motility

Research Articles on ARC16

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Product Notes

The ARC16 arpc5 (Catalog #AAA4751517) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-p16 ARC Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's p16 ARC can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS). WB: 1:500-1:2000 IHC: 1:50-1:100 ICC/IF: 1:50-1:100 IP: 1:50 FC/FACS 1:50. Researchers should empirically determine the suitability of the ARC16 arpc5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p16 ARC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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