Table
p16 ARC Monoclonal Antibody | anti-p16 ARC antibody
p16 ARC
Gene Names
ARPC5; ARC16; p16-Arc; dJ127C7.3
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Flow Cytometry, Functional Assay
Purity
ProA affinity purified
Synonyms
p16 ARC; Monoclonal Antibody; Actin relatated protein 2/3 complex subunit 5 (16kd) antibody; Actin related protein 2/3 complex subunit 5 antibody; Actin related protein 2/3 complex; Subunit 5 16kDa antibody; ARC16 antibody; Arp2/3 complex 16kDa subunit antibody.; anti-p16 ARC antibody
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG
Clone Number
SR34-02
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol
Sequence Length
154
Applicable Applications for anti-p16 ARC antibody
WB, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
Application Notes
WB: 1:1000-1:2000
ICC: 1:50
IHC: 1:50-1:200
FC: 1:50-1:100
ICC: 1:50
IHC: 1:50-1:200
FC: 1:50-1:100
Immunogen
Recombinant Protein
Preservative
0.05% Sodium Azide.
Positive Control
N2A, MCF-7, SK-BR-3, human spleen tissue, mouse lung tissue, mouse spleen tissue.
Subcellular Location
Nucleus
Preparation and Storage
Store at 4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Table
Table
Related Product Information for anti-p16 ARC antibody
The Arp2/3 (Actin-related protein 2/3) complex consits of seven subunits, all which are actin related proteins. The complex is involved in the control of actinpolymerization and in mediating the formation of branched actin networks. p16-ARC, also known as ARPC5 (Actin-related protein 2/3 complex subunit 5) or ARC16 (Arp2/3 complex 16kDa subunit), is a 151 amino acid of the Arp2/3 complex. Thought to play a role in maintaining the intergrity of Arp2/3, p16-ARC is a substrate for MAPKAPLK-2 which, through phosphorylation of p16-ARC, may participate in Arp2/3 regulatory functions and remodeling of the Actin cytoskeleton. Two isoforms of p16-ARC exist due to alternative splicing events.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16 kDa
NCBI Official Full Name
actin-related protein 2/3 complex subunit 5 isoform 2
NCBI Official Synonym Full Names
actin related protein 2/3 complex subunit 5
NCBI Official Symbol
ARPC5
NCBI Official Synonym Symbols
ARC16; p16-Arc; dJ127C7.3
NCBI Protein Information
actin-related protein 2/3 complex subunit 5
UniProt Protein Name
Actin-related protein 2/3 complex subunit 5
UniProt Gene Name
ARPC5
UniProt Synonym Gene Names
ARC16; p16-ARC
NCBI Description
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Uniprot Description
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Research Articles on p16 ARC
Similar Products
Product Notes
The p16 ARC arpc5 (Catalog #AAA8533685) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The p16 ARC reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's p16 ARC can be used in a range of immunoassay formats including, but not limited to, WB, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS). WB: 1:1000-1:2000 ICC: 1:50 IHC: 1:50-1:200 FC: 1:50-1:100. Researchers should empirically determine the suitability of the p16 ARC arpc5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p16 ARC, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
