Rat Discs, Large Homolog 4 (DLG4) ELISA Kit | DLG4 elisa kit

Rat Discs, Large Homolog 4 (DLG4) ELISA Kit

Cat. Num. AAA452613

• Gene Names: Dlg4; Dlgh4; PSD95; Sap90
• Reactivity: Rat
• Synonyms: Discs; Large Homolog 4 (DLG4); Rat Discs; Large Homolog 4 (DLG4) ELISA Kit; PSD95; SAP90; Postsynaptic density protein 95; Synapse-associated protein 90; DLG4 elisa kit

• Reactivity: Rat
• Sequence Length: 724

• Samples: Tissue homogenates, cell lysates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.312-20ng/mL
• Sensitivity: 0.112ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 9665227
• NCBI GeneID: 29495
• NCBI Accession #: NP_062567.1
• NCBI GenBank Nucleotide #: NM_019621.1
• UniProt Accession #: P31016; P97631
• Molecular Weight: – Da
• NCBI Official Full Name: disks large homolog 4
• NCBI Official Synonym Full Names: discs large MAGUK scaffold protein 4
• NCBI Official Symbol: Dlg4
• NCBI Official Synonym Symbols: Dlgh4; PSD95; Sap90
• NCBI Protein Information: disks large homolog 4
• UniProt Protein Name: Disks large homolog 4
• Protein Family: Disks large
• UniProt Gene Name: Dlg4
• UniProt Synonym Gene Names: Dlgh4; Psd95; PSD-95; SAP-90; SAP90

NCBI Description

a molecular scaffolding protein that binds and clusters N-methyl-D-aspartate receptors at neuronal synapses; may be involved in guanine nucleotide-mediated signal transduction pathway [RGD, Feb 2006]

Uniprot Description

Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.