Immunocytochemistry (ICC)
(Immunocytochemistry Analysis: Confocal fluorescent analysis of PC12 using MBS600259 (Red). Actin filaments have been labeled with AlexaFluor® 488 -Phalloidin (Green). Nuclear is stained with DAPI (Blue). Membrane staining positive.)
Mouse Postsynaptic Density Protein 95 Monoclonal Antibody | anti-PSD-95 antibody
Postsynaptic Density Protein 95 (PSD-95, PSD95, Discs Large Homolog 4, DLG4, Post-synaptic Density Protein 95, Synapse-associated Protein 90, SAP90, SAP-90) (MaxLight 750)
Gene Names
Dlg4; Dlgh4; PSD95; Sap90
Reactivity
Bovine, Mouse, Rat
Applications
Immunocytochemistry, Western Blot
Purity
Purified
Synonyms
Postsynaptic Density Protein 95; Monoclonal Antibody; Postsynaptic Density Protein 95 (PSD-95; PSD95; Discs Large Homolog 4; DLG4; Post-synaptic Density Protein 95; Synapse-associated Protein 90; SAP90; SAP-90) (MaxLight 750); anti-PSD-95 antibody
Host
Mouse
Reactivity
Bovine, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
2Q129
Specificity
Recognizes a protein of ~100kD, which corresponds to the apparent MW of PSD-95. A slightly higher MW band is also detected. In rat brain and mouse brain tissue extracts a band of ~75kD is also present. Species Crossreactivity: Rat, mouse and bovine
Purity/Purification
Purified
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Applicable Applications for anti-PSD-95 antibody
Immunocytochemistry (ICC), Western Blot (WB)
Immunogen
Recombinant protein corresponding to rat PSD-95.
Conjugate
MaxLight750
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Immunocytochemistry (ICC)
(Immunocytochemistry Analysis: Confocal fluorescent analysis of PC12 using MBS600259 (Red). Actin filaments have been labeled with AlexaFluor® 488 -Phalloidin (Green). Nuclear is stained with DAPI (Blue). Membrane staining positive.)
Immunocytochemistry (ICC)
(Immunocytochemistry Analysis: Confocal fluorescent analysis of PC12 using MBS600259 (Red). Actin filaments have been labeled with AlexaFluor® 488 -Phalloidin (Green). Nuclear is stained with DAPI (Blue). Membrane staining positive.)
Product Categories/Family for anti-PSD-95 antibody
References
Cho et. al., Neuron. (1992) 9:929-942. Kornau et. al., Science (1995) 269:1737-1740. Kennedy et. al., Trends in Neurosci. (1997) 6:264-268.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
– Da
NCBI Official Full Name
disks large homolog 4
NCBI Official Synonym Full Names
discs large MAGUK scaffold protein 4
NCBI Official Symbol
Dlg4
NCBI Official Synonym Symbols
Dlgh4; PSD95; Sap90
NCBI Protein Information
disks large homolog 4
UniProt Protein Name
Disks large homolog 4
UniProt Gene Name
Dlg4
UniProt Synonym Gene Names
Dlgh4; Psd95; PSD-95; SAP-90; SAP90
NCBI Description
a molecular scaffolding protein that binds and clusters N-methyl-D-aspartate receptors at neuronal synapses; may be involved in guanine nucleotide-mediated signal transduction pathway [RGD, Feb 2006]
Uniprot Description
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.
Research Articles on PSD-95
Similar Products
Product Notes
The PSD-95 dlg4 (Catalog #AAA6247110) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Postsynaptic Density Protein 95 (PSD-95, PSD95, Discs Large Homolog 4, DLG4, Post-synaptic Density Protein 95, Synapse-associated Protein 90, SAP90, SAP-90) (MaxLight 750) reacts with Bovine, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Postsynaptic Density Protein 95 can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Western Blot (WB). Researchers should empirically determine the suitability of the PSD-95 dlg4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Postsynaptic Density Protein 95, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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