Rat Disks large homolog 4 ELISA Kit | Dlg4 elisa kit

Rat Disks large homolog 4 ELISA Kit

Cat. Num. AAA2887751

• Gene Names: Dlg4; Dlgh4; PSD95; Sap90
• Reactivity: Rat
• Synonyms: Disks large homolog 4; Rat Disks large homolog 4 ELISA Kit; Postsynaptic density protein 95; PSD-95; Synapse-associated protein 90; SAP-90; SAP90; Dlg4; Dlgh4; Psd95; Dlg4 elisa kit

• Reactivity: Rat
• Specificity: This assay recognizes recombinant and natural rat Disks large homolog 4. No significant cross-reactivity or interference was observed.
• Sequence Length: 724

• Samples: Serum, Plasma, tissue homogenates and Cell culture supernates and Other biological fluids
• Detection Range: 0.15 ng/mL -10.0 ng/mL.
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for Dlg4 elisa kit

Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of rat Disks large homolog 4 concentrations in serum, Plasma, tissue homogenates and Cell culture supernates and Other biological fluids.

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to Disks large homolog 4. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated polyclonal antibody preparation specific for Disks large homolog 4 and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain Disks large homolog 4, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of Disks large homolog 4 in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 9665227
• NCBI GeneID: 29495
• NCBI Accession #: NP_062567.1
• NCBI GenBank Nucleotide #: NM_019621.1
• UniProt Accession #: P31016; P97631
• Molecular Weight: – Da
• NCBI Official Full Name: disks large homolog 4
• NCBI Official Synonym Full Names: discs large homolog 4
• NCBI Official Symbol: Dlg4
• NCBI Official Synonym Symbols: Dlgh4; PSD95; Sap90
• NCBI Protein Information: disks large homolog 4
• UniProt Protein Name: Disks large homolog 4
• Protein Family: Disks large
• UniProt Gene Name: Dlg4
• UniProt Synonym Gene Names: Dlgh4; Psd95; PSD-95; SAP-90; SAP90
• UniProt Entry Name: DLG4_RAT

NCBI Description

a molecular scaffolding protein that binds and clusters N-methyl-D-aspartate receptors at neuronal synapses; may be involved in guanine nucleotide-mediated signal transduction pathway [RGD, Feb 2006]

Uniprot Description

Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.