Mouse Nodal Homolog (NODAL) ELISA Kit | NODAL elisa kit

Mouse Nodal Homolog (NODAL) ELISA Kit

Cat. Num. AAA451592

• Gene Names: Nodal; Tg.413d
• Reactivity: Mouse
• Synonyms: Nodal Homolog (NODAL); Mouse Nodal Homolog (NODAL) ELISA Kit; NODAL elisa kit

• Reactivity: Mouse
• Sequence Length: 354

• Samples: Serum, plasma, tissue homogenates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 15.625-1000pg/mL
• Sensitivity: 6.2pg/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 218156277
• NCBI GeneID: 18119
• NCBI Accession #: NP_038639.2
• NCBI GenBank Nucleotide #: NM_013611.5
• UniProt Accession #: P43021; Q8BH87
• Molecular Weight: 40,476 Da
• NCBI Official Full Name: nodal preproprotein
• NCBI Official Synonym Full Names: nodal
• NCBI Official Symbol: Nodal
• NCBI Official Synonym Symbols: Tg.413d
• NCBI Protein Information: nodal
• UniProt Protein Name: Nodal
• Protein Family: Nodal
• UniProt Gene Name: Nodal

NCBI Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. Homozygous knockout mice for this gene exhibit early embryonic lethality, while expression of a hypomorphic allele results in defects in anteroposterior and left-right patterning. [provided by RefSeq, Aug 2016]

Uniprot Description

Essential for mesoderm formation and axial patterning during embryonic development.