ELISA (EIA)
(Figure 1. Titration curves of anti-spike neutralization antibody (MBS434300). 96-well corning ELISA plate was coated with SARS-CoV-2 spike RBD protein (MBS434291) at a concentration of 2 ug/ml, and with a EC50 of 12.19 ng/ml. )
COVID 19 Spike Protein (South Africa Variant) Neutralization Coronavirus Monoclonal Antibody | anti-COVID-19 antibody
Anti-Spike Protein (SARS-CoV-2/South Africa Variant) Neutralization Antibody
Applications
ELISA, Neutralization Assay, Immunofluorescence, Flow Cytometry, Functional Assay
Purity
Affinity chromatography
Synonyms
COVID 19 Spike Protein (South Africa Variant) Neutralization Coronavirus; Monoclonal Antibody; Anti-Spike Protein (SARS-CoV-2/South Africa Variant) Neutralization Antibody; 2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Spike Protein; South Africa Variant; Neutralization; anti-COVID-19 antibody
Clonality
Monoclonal
Isotype
Human IgG
Specificity
Reacts with RBD domain of spike protein of SARS-CoV-2, including South Africa variant (B.1.351) and UK variant (B.1.1.7).
Purity/Purification
Affinity chromatography
Form/Format
1 ug/ul in PBS with 40% glycerol
Concentration
1 ug/ul (varies by lot)
Applicable Applications for anti-COVID-19 antibody
ELISA (EIA), Neutralization Assay, Immunofluorescence (IF), Flow Cytometry (FC/FACS)
Application Notes
May be used for other applications, such as WB, IF, etc.
Immunogen
Recombinant spike protein of SARS-CoV-2 South Africa variant
Preparation and Storage
Store at -20 degree C; Stable for 6-months from the date of shipment when kept at 4 degree C. Non-hazardous. No MSDS required.
ELISA (EIA)
(Figure 1. Titration curves of anti-spike neutralization antibody (MBS434300). 96-well corning ELISA plate was coated with SARS-CoV-2 spike RBD protein (MBS434291) at a concentration of 2 ug/ml, and with a EC50 of 12.19 ng/ml. )
ELISA (EIA)
(Figure 1. Titration curves of anti-spike neutralization antibody (MBS434300). 96-well corning ELISA plate was coated with SARS-CoV-2 spike RBD protein (MBS434291) at a concentration of 2 ug/ml, and with a EC50 of 12.19 ng/ml. )
ELISA (EIA)
(Figure 2. Pseudoviral particle (PP) infection assay challenged by neutralizing antibody (MBS434300). HEK293-ACE2 cells infected with SARS-CoV-2 pseudoviral particles under various amounts of neutralizing antibodies, with IC50 of 42.8 ng/ml (MBS434278) and 45 ng/ml (MBS434287))
ELISA (EIA)
(Figure 2. Pseudoviral particle (PP) infection assay challenged by neutralizing antibody (MBS434300). HEK293-ACE2 cells infected with SARS-CoV-2 pseudoviral particles under various amounts of neutralizing antibodies, with IC50 of 42.8 ng/ml (MBS434278) and 45 ng/ml (MBS434287))
Related Product Information for anti-COVID-19 antibody
Human monoclonal anti-spike neutralization (SARS-CoV-2/South Africa Variant) antibody
Severe acute respiratory syndrome coronavirus 2 (SARS?CoV?2) is the virus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the COVID-19 pandemic. There are many thousands of variants of SARS-CoV-2 have been identified throughout the world since it was first identified Wuhan China from late 2019.
The genome of SARS-CoV-2 has 89% nucleotide identity with bat SARS-like-CoVZXC21 and 82% with that of human SARS-CoV. The phylogenetic trees of their orf1a/b, Spike, Envelope, Membrane and Nucleoprotein also clustered closely with those of the bat, civet and human SARS coronaviruses. However, the external subdomain of Spike's receptor binding domain (RBD) of SARS-CoV-2 shares only 40% amino acid identity with other SARS-related coronaviruses.
Severe acute respiratory syndrome coronavirus 2 (SARS?CoV?2) is the virus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the COVID-19 pandemic. There are many thousands of variants of SARS-CoV-2 have been identified throughout the world since it was first identified Wuhan China from late 2019.
The genome of SARS-CoV-2 has 89% nucleotide identity with bat SARS-like-CoVZXC21 and 82% with that of human SARS-CoV. The phylogenetic trees of their orf1a/b, Spike, Envelope, Membrane and Nucleoprotein also clustered closely with those of the bat, civet and human SARS coronaviruses. However, the external subdomain of Spike's receptor binding domain (RBD) of SARS-CoV-2 shares only 40% amino acid identity with other SARS-related coronaviruses.
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Product Notes
The COVID-19 (Catalog #AAA434300) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's COVID 19 Spike Protein (South Africa Variant) Neutralization Coronavirus can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Neutralization Assay, Immunofluorescence (IF), Flow Cytometry (FC/FACS). May be used for other applications, such as WB, IF, etc. Researchers should empirically determine the suitability of the COVID-19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COVID 19 Spike Protein (South Africa Variant) Neutralization Coronavirus, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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