BCAP31 / BAP31 Blocking Peptide | BCAP31 blocking peptide
BCAP31 / BAP31 Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16. [provided by RefSeq, Jan 2012]
Uniprot Description
BCAP31 iso2: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis. Homodimer and heterodimer with BCAP29. Binds CASP8 (isoform 9) as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1. Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1 and non-muscle myosin II. Interacts with PTPLB. Ubiquitous. Belongs to the BCAP29/BCAP31 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: Xq28
Cellular Component: cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; integral to plasma membrane; lipid particle; membrane; translocon complex
Molecular Function: protein binding
Biological Process: antigen processing and presentation of peptide antigen via MHC class I; cell structure disassembly during apoptosis; elevation of cytosolic calcium ion concentration; elevation of mitochondrial calcium ion concentration; ER to Golgi vesicle-mediated transport; positive regulation of caspase activity; reduction of endoplasmic reticulum calcium ion concentration
Disease: Deafness, Dystonia, And Cerebral Hypomyelination
Research Articles on BCAP31
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Product Notes
The BCAP31 bcap31 (Catalog #AAA425294) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The BCAP31 / BAP31 Immunizing Peptide reacts with Human, Dog, Pig, Cow and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-QAAVDGPM DKKEE. It is sometimes possible for the material contained within the vial of "BCAP31 / BAP31, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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