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Goat DEFB106A/DEF106B Polyclonal Antibody | anti-DEFB106A antibody

Goat anti-DEFB106A/DEF106B (aa47-59) Antibody

Gene Names
DEFB106A; BD-6; DEFB-6; DEFB106
Reactivity
Expected from sequence similarity: Human
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
DEFB106A/DEF106B; Polyclonal Antibody; Goat anti-DEFB106A/DEF106B (aa47-59) Antibody; DEFB106A; defensin; beta 106A; BD-6; DEFB-6; DEFB106; MGC118938; MGC118939; MGC118940; MGC118941; MGC133011; MGC133012; beta-defensin 106; beta-defensin 6; beta 6; DEF106B; BD-6 antibody; beta-defensin 106 antibody; beta-defensin 6 antibody; DEF106B antibody; DEFB106 antibody; DEFB-6 antibody; beta 106A antibody; beta 6 antibody; MGC118938 antibody; MGC118939 antibody; MGC118940 antibody; MGC118941 antibody; MGC133011 antibody; MGC133012 antibody; DEFB106A antibody; DEFB106A / DEF106B (aa47-59); anti-DEFB106A antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Expected from sequence similarity: Human
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
CQKSLKCCRTIQP
Sequence Length
65
Applicable Applications for anti-DEFB106A antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Not yet tested - our routinely used western blotting protocol does not allow detection of proteins smaller than the calculated size of 7.37kDa according to the precursor NP_689464.1. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.
Immunogen
Peptide with sequence CQKSLKCCRTIQP, from the internal region (near C Terminus) of the protein sequence according to NP_689464.1; NP_001035794.1.
Epitope
Internal region (near C Terminus)
Note
Reported DEFB106A (NP_689464.1) and DEF106B (NP_001035794.1) are identical.
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
beta-defensin 106
NCBI Official Synonym Full Names
defensin beta 106A
NCBI Official Symbol
DEFB106A
NCBI Official Synonym Symbols
BD-6; DEFB-6; DEFB106
NCBI Protein Information
beta-defensin 106
UniProt Protein Name
Beta-defensin 106
Protein Family
UniProt Gene Name
DEFB106A
UniProt Synonym Gene Names
BD6; DEFB106; DEFB6; BD-6; DEFB-6
UniProt Entry Name
D106A_HUMAN

NCBI Description

Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 106, DEFB106A and DEFB106B, in head-to-head orientation. This gene, DEFB106A, represents the more centromeric copy. [provided by RefSeq, Oct 2014]

Uniprot Description

Defb15: Has antibacterial activity. Belongs to the beta-defensin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: cell surface; extracellular region

Biological Process: defense response to bacterium; innate immune response

Research Articles on DEFB106A

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Product Notes

The DEFB106A defb106a (Catalog #AAA422647) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-DEFB106A/DEF106B (aa47-59) Antibody reacts with Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's DEFB106A/DEF106B can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Not yet tested - our routinely used western blotting protocol does not allow detection of proteins smaller than the calculated size of 7.37kDa according to the precursor NP_689464.1. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product. Researchers should empirically determine the suitability of the DEFB106A defb106a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: CQKSLKCCRT IQP. It is sometimes possible for the material contained within the vial of "DEFB106A/DEF106B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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