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Goat RER1 Polyclonal Antibody | anti-RER1 antibody

Goat anti-RER1 Antibody

Reactivity
Tested: Human; Expected from sequence similarity: Human
Applications
ELISA, Immunohistochemistry
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
RER1; Polyclonal Antibody; Goat anti-RER1 Antibody; RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae); RP4-740C4.2; RER1 homolog; RER1 retention in endoplasmic reticulum 1; RER1 antibody; RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae) antibody; RP4-740C4.2 antibody; RER1 homolog antibody; RER1 retention in endoplasmic reticulum 1 antibody; anti-RER1 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Tested: Human; Expected from sequence similarity: Human
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
HGKRRYRGKEDAGK
Sequence Length
196
Applicable Applications for anti-RER1 antibody
Peptide ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Preliminary experiments gave an approx 45kDa band in Human Brain lysates after 0. 01ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 22.9kDa according to NP_008964.3. The 45kDa band was successfully blocked by incubation with the immunizing peptide.
Immunogen
Peptide with sequence C-HGKRRYRGKEDAGK, from the C Terminus of the protein sequence according to NP_008964.3.
Epitope
C Terminus
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22,958 Da
NCBI Official Full Name
protein RER1
NCBI Official Synonym Full Names
retention in endoplasmic reticulum sorting receptor 1
NCBI Official Symbol
RER1
NCBI Protein Information
protein RER1
UniProt Protein Name
Protein RER1
Protein Family
UniProt Gene Name
RER1
UniProt Entry Name
RER1_HUMAN

NCBI Description

The protein encoded by this gene is a multi-pass membrane protein that is localized to the golgi apparatus. It is involved in the retention of endoplasmic reticulum (ER) membrane proteins in the ER and retrieval of ER membrane proteins from the early Golgi compartment to facilitate gamma-secretase complex assembly. [provided by RefSeq, Oct 2009]

Uniprot Description

RER1: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment. Belongs to the RER1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p36

Cellular Component: cell surface; ER-Golgi intermediate compartment; Golgi apparatus; integral to Golgi membrane; plasma membrane

Molecular Function: acetylcholine receptor binding

Biological Process: retrograde vesicle-mediated transport, Golgi to ER

Research Articles on RER1

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Product Notes

The RER1 rer1 (Catalog #AAA421544) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-RER1 Antibody reacts with Tested: Human; Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's RER1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Immunohistochemistry (IHC). Peptide ELISA: Antibody detection limit dilution 1: 128000. Western Blot: Preliminary experiments gave an approx 45kDa band in Human Brain lysates after 0. 01ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 22.9kDa according to NP_008964.3. The 45kDa band was successfully blocked by incubation with the immunizing peptide. Researchers should empirically determine the suitability of the RER1 rer1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: HGKRRYRGKE DAGK. It is sometimes possible for the material contained within the vial of "RER1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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