Goat Sprouty Polyclonal Antibody | anti-SPRY1 antibody
Goat anti-Sprouty Antibody
Gene Names
SPRY1; hSPRY1
Reactivity
Tested: Human, Mouse; Expected from sequence similarity: Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
Sprouty; Polyclonal Antibody; Goat anti-Sprouty Antibody; SPRY1; hSPRY1; sprouty homolog 1; antagonist of FGF signaling (Drosophila); sprouty (Drosophila) homolog 1 (antagonist of FGF signaling); sprouty; Drosophila; homolog of; 1 (antagonist of FGF signaling); SPRY1 antibody; hSPRY1 antibody; antagonist of FGF signaling (Drosophila) antibody; sprouty (Drosophila) homolog 1 (antagonist of FGF signaling) antibody; 1 (antagonist of FGF signaling) antibody; anti-SPRY1 antibody
Host
Goat
Reactivity
Tested: Human, Mouse; Expected from sequence similarity: Human
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
CPSRGQGKPS
Sequence Length
319
Applicable Applications for anti-SPRY1 antibody
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 16000.
Immunohistochemistry: This product has been successfully used by anonymous customers in paraffin embedded Mouse Brain, showing nuclear staining. Recommended concentration: 1-3ug/ml.
Western Blot: This product has been successfully used in ERMS cells. Recommended concentration: 1-3ug/ml.
Immunohistochemistry: This product has been successfully used by anonymous customers in paraffin embedded Mouse Brain, showing nuclear staining. Recommended concentration: 1-3ug/ml.
Western Blot: This product has been successfully used in ERMS cells. Recommended concentration: 1-3ug/ml.
Immunogen
Peptide with sequence CPSRGQGKPS, from the C Terminus of the protein sequence according to NP_005832.1; NP_955359.1.
Epitope
C Terminus
Note
NP_005832.1 and NP_955359.1 represent varients of the same protein.
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35,122 Da
NCBI Official Full Name
protein sprouty homolog 1
NCBI Official Synonym Full Names
sprouty RTK signaling antagonist 1
NCBI Official Symbol
SPRY1
NCBI Official Synonym Symbols
hSPRY1
NCBI Protein Information
protein sprouty homolog 1
UniProt Protein Name
Protein sprouty homolog 1
Protein Family
UniProt Gene Name
SPRY1
UniProt Synonym Gene Names
Spry-1
UniProt Entry Name
SPY1_HUMAN
Uniprot Description
SPRY1: May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. Belongs to the sprouty family. Induced by FGF signaling.
Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold; Inhibitor
Chromosomal Location of Human Ortholog: 4q28.1
Cellular Component: cytoplasm; cytosol; Golgi apparatus; nucleoplasm; plasma membrane
Molecular Function: protein binding
Biological Process: establishment of mitotic spindle orientation; induction of an organ; metanephros development; negative regulation of cell proliferation; negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of fibroblast growth factor receptor signaling pathway; negative regulation of MAP kinase activity; negative regulation of nerve growth factor receptor signaling pathway; negative regulation of Ras protein signal transduction; ureteric bud development
Research Articles on SPRY1
Similar Products
Product Notes
The SPRY1 spry1 (Catalog #AAA421173) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Sprouty Antibody reacts with Tested: Human, Mouse; Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's Sprouty can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Peptide ELISA: Antibody detection limit dilution 1: 16000. Immunohistochemistry: This product has been successfully used by anonymous customers in paraffin embedded Mouse Brain, showing nuclear staining. Recommended concentration: 1-3ug/ml. Western Blot: This product has been successfully used in ERMS cells. Recommended concentration: 1-3ug/ml. Researchers should empirically determine the suitability of the SPRY1 spry1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: CPSRGQGKPS. It is sometimes possible for the material contained within the vial of "Sprouty, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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