Western Blot (WB)
(Western Blot: Sample: Human MCF7 cell lysate; Primary Ab: 4ug/ml Mouse Anti-Human CNX Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )
Mouse anti-Human Calnexin (CNX) Monoclonal Antibody | anti-CNX antibody
Monoclonal Antibody to Calnexin (CNX)
Immunohistochemistry: 5-30ug/mL
Immunocytochemistry: 5-30ug/mL
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot: Sample: Human MCF7 cell lysate; Primary Ab: 4ug/ml Mouse Anti-Human CNX Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Human MCF7 cell lysate; Primary Ab: 4ug/ml Mouse Anti-Human CNX Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Recombinant CNX, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant CNX, Human.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
Calnexin: a calcium-binding protein of the calreticulin family. A type I membrane protein of the endoplasmic reticulum .Interacts with newly synthesized glycoproteins in the endoplasmic reticulum. May act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.
Protein type: Calcium-binding; Endoplasmic reticulum; Membrane protein, integral; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5q35.3
Cellular Component: axon; cell soma; dendrite cytoplasm; dendritic spine; endoplasmic reticulum; endoplasmic reticulum lumen; endoplasmic reticulum membrane; ER-mitochondrion membrane contact site; extracellular exosome; extracellular matrix; integral component of lumenal side of endoplasmic reticulum membrane; melanosome; membrane; myelin sheath; protein complex; ribosome; rough endoplasmic reticulum; smooth endoplasmic reticulum
Molecular Function: apolipoprotein binding; calcium ion binding; carbohydrate binding; ionotropic glutamate receptor binding; protein binding; RNA binding; unfolded protein binding
Biological Process: aging; antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; clathrin-dependent endocytosis; protein folding; protein secretion; synaptic vesicle endocytosis
Research Articles on CNX
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Product Notes
The CNX canx (Catalog #AAA2090611) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to Calnexin (CNX) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Calnexin (CNX) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). Western Blot: 0.5-5ug/mL Immunohistochemistry: 5-30ug/mL Immunocytochemistry: 5-30ug/mL. Researchers should empirically determine the suitability of the CNX canx for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Calnexin (CNX), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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