Goat Plexin D1 Polyclonal Antibody | anti-PLXND1 antibody
Goat anti-Plexin D1 Antibody
Immunohistochemistry: A customer reported specific stain in Paraffin-embedded Mouse Brain after epitope retrieval in Citrate buffer pH6.
Western Blot: A customer reported a 250kDa band in Human Artherial endothelial cells lysates at 0.5ug/ml.
NCBI and Uniprot Product Information
Uniprot Description
PLXND1: Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature. Mediates anti-angiogenic signaling in response to SEMA3E. Belongs to the plexin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, misc.; Membrane protein, integral
Chromosomal Location of Human Ortholog: 3q22.1
Cellular Component: integral to plasma membrane; lamellipodium; plasma membrane
Molecular Function: protein binding; protein domain specific binding; semaphorin receptor activity
Biological Process: angiogenesis; branchiomotor neuron axon guidance; endothelial cell migration; patterning of blood vessels; positive regulation of protein binding; regulation of angiogenesis; regulation of axon extension involved in axon guidance; regulation of cell migration; synaptogenesis
Research Articles on PLXND1
Similar Products
Product Notes
The PLXND1 plxnd1 (Catalog #AAA420760) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Plexin D1 Antibody reacts with Tested: Human, Mouse; Expected from sequence similarity: Human, Dog, Pig, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's Plexin D1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Peptide ELISA: Antibody detection limit dilution 1: 128000. Immunohistochemistry: A customer reported specific stain in Paraffin-embedded Mouse Brain after epitope retrieval in Citrate buffer pH6. Western Blot: A customer reported a 250kDa band in Human Artherial endothelial cells lysates at 0.5ug/ml. Researchers should empirically determine the suitability of the PLXND1 plxnd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: LAEPKKSHRQ SH. It is sometimes possible for the material contained within the vial of "Plexin D1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
