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Degenerative Spermatocyte Homolog 2 Peptide | DEGS2 peptide

Degenerative Spermatocyte Homolog 2

Gene Names
DEGS2; DES2; FADS8; C14orf66
Reactivity
Human
Applications
Western Blot
Synonyms
Degenerative Spermatocyte Homolog 2; DEGS2; Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2; DEGS2 peptide
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Form/Format
Provided as solution in phosphate buffered saline
Sequence Length
323
Applicable Applications for DEGS2 peptide
Western Blot (WB)
Immunogen
Synthetic peptide derived from human DEGS2 protein.
Positive Control
Highly expressed in skin, intestine and kidney.
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Related Product Information for DEGS2 peptide
Bifunctional enzyme which acts as both a sphingolipid delta(4)-desaturase and a sphingolipid C4-hydroxylase. Up-regulated during keratinocyte differentiation. Not expressed at day 0 or day 3 after differentiation, detected on day 6 and increases by day 9. Belongs to the fatty acid desaturase family. DEGS subfamily. Highly expressed in skin, intestine and kidney.
Product Categories/Family for DEGS2 peptide

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37 kDa
NCBI Official Full Name
sphingolipid delta(4)-desaturase/C4-hydroxylase DES2
NCBI Official Synonym Full Names
delta(4)-desaturase, sphingolipid 2
NCBI Official Symbol
DEGS2
NCBI Official Synonym Symbols
DES2; FADS8; C14orf66
NCBI Protein Information
sphingolipid delta(4)-desaturase/C4-hydroxylase DES2; sphingolipid delta(4)-desaturase/C4-hydroxylase DES2; sphingolipid delta(4)-desaturase 2; sphingolipid C4-hydroxylase/delta 4-desaturase; sphingolipid delta 4 desaturase/C-4 hydroxylase; degenerative spermatocyte homolog 2, lipid desaturase
UniProt Protein Name
Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2
UniProt Gene Name
DEGS2
UniProt Synonym Gene Names
C14orf66
UniProt Entry Name
DEGS2_HUMAN

NCBI Description

This gene encodes a bifunctional enzyme that is involved in the biosynthesis of phytosphingolipids in human skin and in other phytosphingolipid-containing tissues. This enzyme can act as a sphingolipid delta(4)-desaturase, and also as a sphingolipid C4-hydroxylase. [provided by RefSeq, Oct 2008]

Uniprot Description

Function: Bifunctional enzyme which acts as both a sphingolipid delta(4)-desaturase and a sphingolipid C4-hydroxylase

By similarity. UniProtKB Q8R2F2

Pathway: Membrane lipid metabolism; sphingolipid biosynthesis.

Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein

By similarity UniProtKB Q8R2F2.

Tissue specificity: Highly expressed in skin, intestine and kidney. Ref.1

Induction: Up-regulated during keratinocyte differentiation. Not expressed at day 0 or day 3 after differentiation, detected on day 6 and increases by day 9. Ref.1

Sequence similarities: Belongs to the fatty acid desaturase family. DEGS subfamily.

Research Articles on DEGS2

Similar Products

Product Notes

The DEGS2 degs2 (Catalog #AAA396380) is a Peptide produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Degenerative Spermatocyte Homolog 2 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Degenerative Spermatocyte Homolog 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the DEGS2 degs2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Degenerative Spermatocyte Homolog 2, Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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