CD3epsilon Monoclonal Antibody | anti-CD3epsilon antibody
CD3epsilon
Avoid repeated freeze-thaw cycles.
For use within 30 days store at 4°C.
NCBI and Uniprot Product Information
Uniprot Description
CD3E: a T cell surface glycoprotein that is a component of the T cell antigen receptor. The recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation. Contains 1 immunoglobulin-like domain and 1 ITAM domain.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 9 A5.2|9 24.84 cM
Cellular Component: alpha-beta T cell receptor complex; dendritic spine; external side of plasma membrane; immunological synapse; intercellular junction; plasma membrane; T cell receptor complex
Molecular Function: protein binding; protein heterodimerization activity; protein homodimerization activity; SH3 domain binding; signal transducer activity
Biological Process: cell surface receptor linked signal transduction; cerebellum development; dendrite development; lymphocyte activation; negative regulation of smoothened signaling pathway; negative thymic T cell selection; positive regulation of alpha-beta T cell proliferation; positive regulation of calcium-mediated signaling; positive regulation of interferon-gamma production; positive regulation of interleukin-2 biosynthetic process; positive regulation of interleukin-4 production; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of T cell activation; positive regulation of T cell anergy; positive regulation of T cell proliferation; protein homooligomerization; response to nutrient; T cell costimulation; T cell receptor signaling pathway
Research Articles on CD3epsilon
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Product Notes
The CD3epsilon cd3e (Catalog #AAA378111) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD3epsilon can be used in a range of immunoassay formats including, but not limited to, T cell depletion T cell activation; Immunofluorescence; Flow cytometry; Western blot. Researchers should empirically determine the suitability of the CD3epsilon cd3e for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD3epsilon, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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