FtsZ inhibitor C109, Inhibitor
FtsZ inhibitor C109
Purity
>98% (HPLC)
Synonyms
FtsZ inhibitor C109; Compound 10126109; inhibitor
Purity/Purification
>98% (HPLC)
Target
Antibacterial
Receptor
Antibacterial
Chemical Name
methyl 2-((4-nitrobenzo[c][1, 2, 5]thiadiazol-5-yl)thio)acetate
Molecular Formula
C9H7N3O4S2
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Related Product Information for FtsZ inhibitor C109, inhibitor
FtsZ inhibitor C109 (Compound 10126109) is a broad spectrum antibacterial compound that inhibits the cell division protein FtsZ, inhibits the FtsZ GTPase activity with IC50 of 8.2uM; inhibits both the GTPase and polymerization activities of purified B. cenocepacia FtsZ, prevents divisome formation by altering the localization of the essential cell division protein FtsZ; displayes antibacterial activity against Gram-positive and Gram-negative cystic fibrosis pathogens, including Mycobacterium abscessus, C109 effectively cleared B. cenocepacia infection in the Caenorhabditis elegans model and exhibited additive interactions with clinically relevant antibiotics.
Product Categories/Family for FtsZ inhibitor C109, inhibitor
References
1. Hogan AM, et al. Antimicrob Agents Chemother. 2018 Oct 8. pii: AAC.01231-18. doi: 10.1128/AAC.01231-18.
2. Scoffone VC, et al. Front Microbiol. 2015 Aug 5; 6:815. doi: 10.3389/fmicb.2015.00815.
2. Scoffone VC, et al. Front Microbiol. 2015 Aug 5; 6:815. doi: 10.3389/fmicb.2015.00815.
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Product Notes
The FtsZ inhibitor C109 (Catalog #AAA3607099) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "FtsZ inhibitor C109, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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